ID A0A016U676_9BILA Unreviewed; 954 AA.
AC A0A016U676;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Leucine Rich repeat-containing domain protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0054.g2483 {ECO:0000313|EMBL:EYC10660.1};
GN Synonyms=Acey-tol-1 {ECO:0000313|EMBL:EYC10660.1};
GN ORFNames=Y032_0054g2483 {ECO:0000313|EMBL:EYC10660.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC10660.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC10660.1}.
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DR EMBL; JARK01001390; EYC10660.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016U676; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 6.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF13855; LRR_8; 5.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 17.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 7.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..954
FT /note="Leucine Rich repeat-containing domain protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001491977"
SQ SEQUENCE 954 AA; 105942 MW; E050607AC0AE96BF CRC64;
MWLRVAAVFG ILRLTEAFQD CPNGCDCLPD PLVESSFLYV CRWSSLPSDF HFSNSSSIRS
LQIVCEDGFS LPNDLFRGVG GVQHLRIEAC RWAELPDELL APLTNLRSLH LHEVSLAKKA
FTVSDEAIVN LKRLEKLSIT NSNLLQLPEK LFCGLKNLQV LNVSSNWIST LTSADSSCIA
NQLIIVDFSH NRLDRLGAEL NTLPAVRQLS LSNNRLSSIG KDSLLKCPLL QQLELNNNLL
EAVEDLPETL IHINLASNQL SIIPPSVTVL PHLVSLNLSH NSISEDSPSV CITSVLEFLD
LSWNHISALP SRLYPNSMGS LVHLHLEGNQ ISELNPLQLV NYTRLQTLNV ASNRLERLRD
DIFAGLNELS VLRVANNSID TLEPAAFADL ALGDVDLSHN RLTEVPIAIG RLFKLKKIDL
SHNKIRKLHQ FIFNKISHLH TIDLSHNELP SVSPYVFSDC AYLTSLNLSH NHISQLFHDS
LAKCPLLKRI DLSDNRLGSL ADALSQASAV RRLDVSRNRL ELLQWDELPP RLEHLVADSN
IISLLGAAIK SKVRTASLRG NRIEQLSADQ IPDAIETLDL SANRVQHIAS STFAAKTSLR
SLDLSDNRLT QLTEESLIAD GVHSIDASLR GNPLRCSCEL HWIKKPEVVK RKVNIVGISE
TLCTHPVTGK VISLDKVDSK DLLCEYSQVC EPDCVCCQFG NCDCKAVCPP GCSCFRDALF
ETNVVRCENL TETDMKAFSP SAVPISATHV YLSGLSIPIL RSHSFLGRPR LEHLHINASG
IRGIQPKAFN TLPKLKLLDL SDNAIVRLSG DEFHKTSAVS HLFLNGNRLR TVERGLTEKL
PSLTTITLHN NDLTDVSPAL ASSGVRSLSL SGNAFRCDCT PRFSAPMWIH ENRAKVVDMD
RVRCVENVTE SFRNNDTTVL SAYPPNVGHD IFTMPMDGWF YWIYLCYVKE SADN
//
