ID A0A016UC51_9BILA Unreviewed; 984 AA.
AC A0A016UC51;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Tetratricopeptide repeat-like domain-containing protein {ECO:0000259|Pfam:PF09976};
GN Name=Acey_s0047.g1465 {ECO:0000313|EMBL:EYC12412.1};
GN ORFNames=Y032_0047g1465 {ECO:0000313|EMBL:EYC12412.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC12412.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SIMILARITY: Belongs to the TTC21 family.
CC {ECO:0000256|ARBA:ARBA00010935}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC12412.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JARK01001383; EYC12412.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016UC51; -.
DR STRING; 53326.A0A016UC51; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR018704; TPR_21.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR040364; TTC21A/TTC21B.
DR PANTHER; PTHR14699; STI2 PROTEIN-RELATED; 1.
DR PANTHER; PTHR14699:SF0; TETRATRICOPEPTIDE REPEAT PROTEIN 21 HOMOLOG; 1.
DR Pfam; PF09976; TPR_21; 1.
DR Pfam; PF13174; TPR_6; 2.
DR SMART; SM00028; TPR; 9.
DR SUPFAM; SSF48452; TPR-like; 4.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 617..741
FT /note="Tetratricopeptide repeat-like"
FT /evidence="ECO:0000259|Pfam:PF09976"
FT REPEAT 708..741
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 984 AA; 110293 MW; 3B400D2936110151 CRC64;
MDYSDNLLKT IASVHFYLRE GHYGTALKIC GSTEAGTPHI QLLKAIALNL NGRPAEAMRL
LEPLRSGDYA FGALHALKQA HNMAETPDRQ SLLEIESAIS SIRDAPAIAQ YSAAEALFFM
KEYAKAKPFL EKIVKENPDN ALFACLSGWT EISLGRDQKS TVEMFDRAIA GRYLDGYVGK
MAVLAARQLA NEMKALAKDA LAASFGHMPF HVESARACLL AKEWNNTLQA LQNSNIVESD
NVLIQFLLAV HSICSAGTKI ESSLNELQTA IDAAEADNHA LLANMANALY RMGARNRTVL
AFSRELLARA NKRSRRPAYV VDELRVAISL DDVREVTAKV KELMSMDTDD PYAALGVTLS
NLMAGKLDDA SAQFTFMKEA NPNISNFAIY HFASAVITKY KDNSYEKFMS MVNDAIIVHF
DKVQTMPFGV EYLRALDSDF LMGLIYQIMD YAPLVPMKSP NDTLKTAERI LNILIEQSPG
ISQAYYILAR CLFLHSEWDA ADRMIDQCLQ RNETVADAYL LRAEIKLMKG QVADADNCLN
TGLSFNFAIR ESSIFHLIKA KVHKQKNEIE KAADLLKAGL KLPQKERSTN LLARKEGGDG
QRISIQLELI DCLQSLKQMH EAERVMEEAV QQWKGKPEEE QLLLMNAQIH IAKGDVDGAL
ALLSTVQPGQ PNYHSARMKM AEIYLEEKQD KTMFTLCYRE LLKSAPTSAT YALLGDAYMS
VQEPEKAIEA YEMALKMSSK DMALTEKIGE AYVLCHLYSK AVNFYESVMN STKDKRMRLK
LADLLHQLGN TEKCMRILRQ PLDEEPDPID PATISAHVQY LKLLAEVQFE GGKHTEALND
LSAAKNLQMK LLAKNDSVAN QQIKKEISKI LCSQAEIYSN AHDHKMVIER YKEALTYFET
DIKTILALAN RYLTINKLVE CKQLCEMALS IDKNNDEATL MVADMLYTNN DTDKAIVHFA
QLLEKYPRLY GEYQAITRVT QLTA
//
