ID A0A016UGN9_9BILA Unreviewed; 352 AA.
AC A0A016UGN9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein {ECO:0000259|SMART:SM01000};
GN Name=Acey_s0042.g533 {ECO:0000313|EMBL:EYC13793.1};
GN Synonyms=Acey-C01G10.8 {ECO:0000313|EMBL:EYC13793.1};
GN ORFNames=Y032_0042g533 {ECO:0000313|EMBL:EYC13793.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC13793.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SIMILARITY: Belongs to the AHA1 family.
CC {ECO:0000256|ARBA:ARBA00006817}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC13793.1}.
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DR EMBL; JARK01001378; EYC13793.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016UGN9; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0001671; F:ATPase activator activity; IEA:InterPro.
DR GO; GO:0051087; F:protein-folding chaperone binding; IEA:InterPro.
DR CDD; cd08892; SRPBCC_Aha1; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 3.15.10.20; Activator of Hsp90 ATPase Aha1, N-terminal domain; 1.
DR InterPro; IPR036338; Aha1.
DR InterPro; IPR015310; AHSA1-like_N.
DR InterPro; IPR013538; ASHA1-like_C.
DR InterPro; IPR023393; START-like_dom_sf.
DR PANTHER; PTHR13009; HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1; 1.
DR PANTHER; PTHR13009:SF8; LD43819P; 1.
DR Pfam; PF09229; Aha1_N; 1.
DR Pfam; PF08327; AHSA1; 1.
DR SMART; SM01000; Aha1_N; 1.
DR SUPFAM; SSF103111; Activator of Hsp90 ATPase, Aha1; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..352
FT /note="Activator of Hsp90 ATPase AHSA1-like N-terminal
FT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001489292"
FT DOMAIN 38..172
FT /note="Activator of Hsp90 ATPase AHSA1-like N-terminal"
FT /evidence="ECO:0000259|SMART:SM01000"
SQ SEQUENCE 352 AA; 39580 MW; C9420613194F7F13 CRC64;
MGFLFLWASM AKWGEGDPRW IVEERADATN VNNWHWSEKN ATPWSKTRIT DLLEGLTIED
GPICVKLETI KSIEGEATAN NRKAKLIFLY EWDIKIGFLG RVSGSDLEYK GSLEIPNLSD
ENDASEIDVN VSIDTKGPHD AAIRQLLNKA GTSQIRSALA TYIRELKEEF SKGLILPTDK
VKPQVVTKGK TTVIDKKSFQ NMVITDEKGD ASKTVEKFDV KSIELSESYK VPPDRLYEVL
SEPTLVRAWA NGNIEWDFKE GGKFTLFGGT VTGTFDKIKP NEEITMSWRL KAYPANHFAK
IKFILKDESD STSLLVEAEG VPSHMAEETR NGFTRYYLAS IARTFGFSAR MS
//
