ID A0A016UZA4_9BILA Unreviewed; 524 AA.
AC A0A016UZA4;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000259|PROSITE:PS50262};
GN Name=Acey_s0021.g244 {ECO:0000313|EMBL:EYC20495.1};
GN Synonyms=Acey-npr-19 {ECO:0000313|EMBL:EYC20495.1};
GN ORFNames=Y032_0021g244 {ECO:0000313|EMBL:EYC20495.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC20495.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC20495.1}.
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DR EMBL; JARK01001357; EYC20495.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016UZA4; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR22718:SF36; G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22718; SERPENTINE RECEPTOR, CLASS X; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 64..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..514
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 80..356
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 389..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 524 AA; 60574 MW; FBD9BE7FB7B31898 CRC64;
MSNLVRGFVI NATLRYRNDL SGDNAVSPEV TNLRLERTAT MWDKNASYYT LQALLSTWER
RDDLIVVSIW LVMLSYALIS NVLILVGIAR SSTMRTATSY WFIISLAVCD IVMTIISLVH
LVPATAFHDA YVEFYSLRNI LMIFFYDLFW YTGVVQLGLM AGNRFVSIVY PMEYKNMFSR
KRSLYLILFG YFLGFLVSLP TLFPCCHTLW NSDYYITVYQ PMDTWYKYVD MSVNSISLFM
MIMSYAVIIY KVRESGRAMA KYQLTIRTRQ QHALMSGISL SCQMNGCTRM SSVRPPRSQV
SKKEMRLFIQ FFVVSLVFLL TWTTWQWLPH MSGSKWAYFV MTSLFFINNS VNPTVYLLFN
TQLRRELHYL LCRHHAISSV QNKQRRTLFG KHTGNPADIK TKTTTAGEEA TRSLDPAHSL
SSHTTSEDHA KPHLLIQVSS FHTKSSEKIQ KGVWKSCMCE VERRLHQQRN NQRCLAIWIV
DDSRKPHSAR RLLLHMPSCC YVCVQLAAAL FALLQNKSVT SSVT
//
