ID   A0A016VBB9_9BILA        Unreviewed;       565 AA.
AC   A0A016VBB9;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   Name=Acey_s0013.g2082 {ECO:0000313|EMBL:EYC24735.1};
GN   ORFNames=Y032_0013g2082 {ECO:0000313|EMBL:EYC24735.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC24735.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC24735.1}.
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DR   EMBL; JARK01001349; EYC24735.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016VBB9; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR47027; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR47027:SF8; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   DOMAIN          96..350
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   565 AA;  65501 MW;  527315EF7E7C624C CRC64;
     MTALRRPDGT ITSSRRVMEK VIYDFYSDLF DSHVHLPPCH LREDEYVIPS VLPSEVRHAI
     KSVKNRTAPG PDRIRPEHLK NLPTALVNTL ARLFTRYLSE CKVPSQWKTS RTVLLYKKGD
     PQDIGNYRPI CLLSVVYKLF TRVILNRIER TLDEGQPCEQ AGFRKGFSTI DHIHTVTRLI
     EVSREYKMPL CLTFIDLKKA FDTVETEAVL EALGNQGVPT QYIRIFRELY SNFTTRISPF
     YDDITIDVRR GVRQGDTVSP KLFTATLEDV MRRLEWDNMG VRVDGRLLHH LRFADDIVLI
     TPSISQAERM LADFDDACGK IGLQLNLTKT MFMRNGWVPD APFSLNGTTI SECSSYVYLG
     REVNMMNDLA PELGRRKRAA WGAYKSIEDV VKKTKNIRLR AHLFNTTVLP ALTYASETWA
     LRKQDENAVS VIERSIERVM LGMTRLTQVR AGIRSSTLRQ QSKIRDAAVY AKSSKIRWAG
     HVMRLNDHRW TRAVSDWTPR NVKRTTGRPP TRWSDFFTKS FKERYDALRV SRTDRTHWTT
     LARERDKWKD CWRPLGLPDD QRESR
//