ID   A0A016VCV6_9BILA        Unreviewed;       547 AA.
AC   A0A016VCV6;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Sec1 family protein {ECO:0008006|Google:ProtNLM};
GN   Name=Acey_s0012.g1797 {ECO:0000313|EMBL:EYC25270.1};
GN   Synonyms=Acey-vps-45 {ECO:0000313|EMBL:EYC25270.1};
GN   ORFNames=Y032_0012g1797 {ECO:0000313|EMBL:EYC25270.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC25270.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC       {ECO:0000256|ARBA:ARBA00009884}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC25270.1}.
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DR   EMBL; JARK01001348; EYC25270.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016VCV6; -.
DR   STRING; 53326.A0A016VCV6; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.40.60; -; 1.
DR   Gene3D; 3.40.50.1910; -; 1.
DR   Gene3D; 3.40.50.2060; -; 1.
DR   InterPro; IPR043154; Sec-1-like_dom1.
DR   InterPro; IPR043127; Sec-1-like_dom3a.
DR   InterPro; IPR001619; Sec1-like.
DR   InterPro; IPR027482; Sec1-like_dom2.
DR   InterPro; IPR036045; Sec1-like_sf.
DR   PANTHER; PTHR11679:SF3; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45; 1.
DR   PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR   Pfam; PF00995; Sec1; 1.
DR   PIRSF; PIRSF005715; VPS45_Sec1; 1.
DR   SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
SQ   SEQUENCE   547 AA;  62381 MW;  19EE5B4F037C2AF4 CRC64;
     MDVLGTARAY IKEMVNLAGP QMKVILMDKE TTTIVSCAFA QSEMMQKEVY LFERLDSPVP
     REPIKHLKCL VFVRPTPDNV QLLSTELRNP RYAQYYIYFS NIVSKTDLKM LAEADEHETV
     REVHEFFVDG IALSPPLFCI NLKEVYDRSF NLTPSAFLRI KQALVALLLN QKKKPLIRYQ
     RSSEDCKRLA DDLNQVVRRE EGLFDNAKRD TVLLIIDRSE DPVTPLLNQW TYEAMVHELI
     TINNNRVAVD NQSMVLSELH DEFYAKNVSS NFGEIGQNIK LLMNEFQQKS QIHKNLESIA
     DMKNFVEEYP QFKKISGTVS KHVTLVGELS KIVANQNLLE ISEVEQSIVA EGDHSRCLER
     VRTLINHPKT TSLNALRLVL LYALRFEGNP NNDLNGLLNL LRRDVDGANV VRALLRYAGA
     GRRKSDLFGE GSTMEMTKRF IKGLKGVENI YTQHEPYIKT IMENVSRGKL SDQQYPYVTG
     DITNSRQDNL IIFIVGGATF EEALFVRSQN EKRMQGGGGP AVTLATTFMH NTTSFVQQFS
     ISSHWAR
//