ID   A0A016VQL7_9BILA        Unreviewed;       332 AA.
AC   A0A016VQL7;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   Name=Acey_s0006.g3057 {ECO:0000313|EMBL:EYC29596.1};
GN   ORFNames=Y032_0006g3057 {ECO:0000313|EMBL:EYC29596.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC29596.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC29596.1}.
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DR   EMBL; JARK01001342; EYC29596.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016VQL7; -.
DR   STRING; 53326.A0A016VQL7; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR46238; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46238:SF8; RIBONUCLEASE H; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   DOMAIN          1..146
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   COILED          79..106
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   332 AA;  38084 MW;  2ECE09DDAC91D3DD CRC64;
     MALRIHGIPE EYVRWIKMLY SRPTSVVRCA AGTSKPFPVQ VGVHQGSALS PLLFILCVDA
     ITRDIQKPHP WCLLYADDVM LAAETREELQ EEVQLWKERL QRYGLRLNIA KTEYMECGAK
     IEDGTICVDG NNLKKVECFK YLGSRITSTG DVLPDAYGRA NSAWMKWRTT TGILCDKKMP
     IRLKFKVYRT VVRPVALCGT ECWATTKVTR QVLHTMEMRM LRWSMGVTLK DKVSNEMVRS
     TFGVAPIIDK MREARLRWFG HVLRREGGSV AKTALTLEVK GVRPRGRPKT RWLDCVKTDM
     AEVQLTTRDA NNRNKWKKRC STADPATTWD KR
//