ID   A0A016W7P9_9BILA        Unreviewed;       431 AA.
AC   A0A016W7P9;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   Name=Acey_s1078.g3558 {ECO:0000313|EMBL:EYC35332.1};
GN   ORFNames=Y032_1078g3558 {ECO:0000313|EMBL:EYC35332.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC35332.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC35332.1}.
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DR   EMBL; JARK01000678; EYC35332.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016W7P9; -.
DR   STRING; 53326.A0A016W7P9; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   CDD; cd00304; RT_like; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR21301; REVERSE TRANSCRIPTASE; 1.
DR   PANTHER; PTHR21301:SF12; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   DOMAIN          1..164
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   REGION          228..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   431 AA;  48993 MW;  6325058BCD4979E6 CRC64;
     MQLEHNCVVE SFDVTALYTN VSNERALQAI FELLIEYQGN INMHGLAVAQ IMVLLQECLR
     CTIFRWSGNY FAQTRGLAMG QRLAPTLAIA FMSRIEAPVL ELCPLLYCRY IDDCFVVCTT
     QEEMDMCFEL LNNQSEHIKF TREKPKNDWL PFLNVQVHIR GGSRVTKWYR KPNNKNIIVH
     CRSAHPQQMK RAVVKNMFRT AAEVCSGEAE RKESIALAKH IAASNGYKVG GSNARSRRLQ
     APRSKSPKKD KIPFKLPFVS DEVSTAIRRC LRKVNLDSLV TVVDQPPDNL KRQLVRNRLY
     DRFCSTPGCI FCPNGKGGDC MGSGIIYLIS CSECGDEYIG ETARPLCLRI KEHLEGKARS
     RESTPLGAHR LHRHGGADFG VKVSILAHEQ QISARKSLEA FWIHAKNPKM NRKEECLSIT
     RELAPYIRML F
//