ID A0A016WGL3_9BILA Unreviewed; 477 AA.
AC A0A016WGL3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Gustatory receptor {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0740.g1965 {ECO:0000313|EMBL:EYC38133.1};
GN ORFNames=Y032_0740g1965 {ECO:0000313|EMBL:EYC38133.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC38133.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the otopetrin family.
CC {ECO:0000256|ARBA:ARBA00006513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC38133.1}.
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DR EMBL; JARK01000340; EYC38133.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016WGL3; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015252; F:proton channel activity; IEA:InterPro.
DR InterPro; IPR004878; Otopetrin.
DR PANTHER; PTHR21522:SF33; OTOPETRIN-LIKE; 1.
DR PANTHER; PTHR21522; PROTON CHANNEL OTOP; 1.
DR Pfam; PF03189; Otopetrin; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 189..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EYC38133.1"
SQ SEQUENCE 477 AA; 54059 MW; 60996717B43A8703 CRC64;
MQLADDEQTM PKRGSRHSRK FKAMARAFSV LPRKVTSTRK ATVTRNATFT HPTEGCLGAS
APDFSDLQRL DLPRRARRFS SKLHRSGSHR PDFVNTWIRS SNFELCENIQ EEQNETQHPQ
QQPSCRMMAR EKCDSGDDNN GGSVRSAGKM GEISRQDSTL SFESIDDSNE MKNSAEETWK
QSKEAKASLL TALTAFYSLF LTIFALVLEL SHLLSGEEQR EINMKDMIFG AYMYGVSILF
FIYMYVVLLL NPRWYWTINI VERYVKRFKS SDSSISSAVA TVRKVTHCGS SAGSLFLRLG
CVVFGVTGVV YYAFLVFLCT ADKTCPTVST ALDICAIVFI FTQMHFIFCN SKLSITGHHT
AARFGTMHLI AANLWTWIRY VLMEEGVMEK EIREVFQTLN NRSEETMDEE SVEAFEHRDI
DLVGGCRAAE CILGSLSEVM FTAIVEYSLI AAAVMYIVWR NIGRAGHGCE YVKRKHR
//
