ID A0A016WUX9_9BILA Unreviewed; 504 AA.
AC A0A016WUX9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=TFIIS N-terminal domain-containing protein {ECO:0000259|PROSITE:PS51319};
GN Name=Acey_s0515.g2784 {ECO:0000313|EMBL:EYC42848.1};
GN Synonyms=Acey-R03D7.4 {ECO:0000313|EMBL:EYC42848.1};
GN ORFNames=Y032_0515g2784 {ECO:0000313|EMBL:EYC42848.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC42848.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC42848.1}.
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DR EMBL; JARK01000115; EYC42848.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016WUX9; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0070449; C:elongin complex; IEA:InterPro.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.250.3180; -; 1.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR010684; RNA_pol_II_trans_fac_SIII_A.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR15141; TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3; 1.
DR PANTHER; PTHR15141:SF76; TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3; 1.
DR Pfam; PF06881; Elongin_A; 1.
DR Pfam; PF08711; Med26; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 1..77
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 75..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 504 AA; 57536 MW; 47FFC67781ECF0B1 CRC64;
MTVDDAILNK VNKYGKLIKK KEKVAHVLSR LNNIDMTLEI LSATNIGRYV NRLCHDSEYG
RDASRIIEKW KEIARQSGVR GGDEEPASED DEQRARHQSP DPAGASSAGY ESHSKDYDSG
RSRSHHDSGH DGYSNDDSDE HASGKHRRRN GEDMDRYYKE YSRKGDTPKK RRHDERRHHE
QPRYRDERHR DSDSEDGSDQ HHTKRSRDKV VTEFDMILQS ADSGQPKHKK REHHRKWSEL
PVLSNYQPFP QAVRAAKDAA APPADDFNPE NMFKPRNERG KVFAGRRKNI AMSVPSLFNI
CLRVLCNNIG VLLYAEYIPY DVLKPVFEKC TVEELASIES KHPYLEDDSG ELWQRFVTKK
YPGEEPDCDG SWKDLYYFLE KEKEDKLKRL SQRIGKTHQA ETAKGQRKTL LADATAPTYV
RRRQMAHGIA NASRPLPSAI EVSSARRKIF ETGGSKAALA ALPSAVVNRN STVGAKTDRS
SKKPPAKKGA LMIKTMKMLN MKRK
//
