ID A0A017HGG9_9RHOB Unreviewed; 731 AA.
AC A0A017HGG9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Rumeso_04673 {ECO:0000313|EMBL:EYD73552.1};
OS Rubellimicrobium mesophilum DSM 19309.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Rubellimicrobium.
OX NCBI_TaxID=442562 {ECO:0000313|EMBL:EYD73552.1, ECO:0000313|Proteomes:UP000019666};
RN [1] {ECO:0000313|EMBL:EYD73552.1, ECO:0000313|Proteomes:UP000019666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19309 {ECO:0000313|EMBL:EYD73552.1,
RC ECO:0000313|Proteomes:UP000019666};
RA Fiebig A., Goeker M., Klenk H.-P.P.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYD73552.1}.
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DR EMBL; AOSK01000130; EYD73552.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A017HGG9; -.
DR STRING; 442562.Rumeso_04673; -.
DR PATRIC; fig|442562.3.peg.4603; -.
DR HOGENOM; CLU_019564_1_0_5; -.
DR OrthoDB; 9776727at2; -.
DR Proteomes; UP000019666; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR017232; NtrY.
DR InterPro; IPR045671; NtrY-like_N.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF19312; NtrY_N; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PIRSF; PIRSF037532; STHK_NtrY; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000019666};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EYD73552.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 303..356
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 493..713
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 712..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 731 AA; 80238 MW; 0ADFBE81D1873F60 CRC64;
MRNAATLGLV VLGPVLAGLT YVVLGPLDQG ASSTALRIVL LTDLVYVLAI AALVAREVAR
MVAARRAKSA GSRLHLRLVG VFALLALLPT VTVAVFSVLT INVGLEGWFS ERVREVVTNS
MAAAEAYEQE HRQELTRDGE ALAEALDQQK QANVALSDGD IRQALGRMQA QIERGLTEAF
VIDGAGDIRA RGARSYEFAY ERPSDEDFRL AQAEGIRIIE DWPNDEFRAL IPLPSFLDRY
LYVTRAVDGE ILSLLDETKD TVELYRQLDS DKGRLLFEFG LLYLGFAVIL ILAAVWLGLW
FAEGLSKPIG RLLSASQRVG EGDLDVRVIE EEGDDEIAAL GRHFNQMTRQ LKAQRGRLLE
TTEQIEQRRR LFDSVLSSVT SGVVGLDAMG RVTFANRSAQ RLLDVGEAPG RVALAVAVPE
FGPLFDALSQ ESREVVQEQV ALVRGGKQET LLVRMSPRRA DDGSLEGYVV AFDDVTDLVS
AQRMAAWGDV ARRIAHEIKN PLTPIRLSAE RIKRKFRRHL DETAAGDLDQ MTDVIVRQTE
DLRRIVDEFS KFARMPEPDR RDSDLTALVR DAVTLQEAGQ PGVKFVSVLP AAQVPAEVDP
GMISQALTNL IKNAGEAIES YQEQGAEPGF QPVIKVQLQP EGAVARITIE DNGIGLPEDR
ARLFEPYVTT RAKGTGLGLP IVKKIIEEHG GTLQLEDAEG RGARAVIRLP TKARPSIEAD
QPETSQARRA V
//
