ID   A0A017HT09_9RHOB        Unreviewed;       361 AA.
AC   A0A017HT09;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=3-isopropylmalate dehydrogenase {ECO:0000313|EMBL:EYD76894.1};
DE            EC=1.1.1.85 {ECO:0000313|EMBL:EYD76894.1};
GN   ORFNames=Rumeso_01416 {ECO:0000313|EMBL:EYD76894.1};
OS   Rubellimicrobium mesophilum DSM 19309.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Rubellimicrobium.
OX   NCBI_TaxID=442562 {ECO:0000313|EMBL:EYD76894.1, ECO:0000313|Proteomes:UP000019666};
RN   [1] {ECO:0000313|EMBL:EYD76894.1, ECO:0000313|Proteomes:UP000019666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19309 {ECO:0000313|EMBL:EYD76894.1,
RC   ECO:0000313|Proteomes:UP000019666};
RA   Fiebig A., Goeker M., Klenk H.-P.P.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC       dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYD76894.1}.
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DR   EMBL; AOSK01000039; EYD76894.1; -; Genomic_DNA.
DR   RefSeq; WP_037278711.1; NZ_KK088557.1.
DR   AlphaFoldDB; A0A017HT09; -.
DR   STRING; 442562.Rumeso_01416; -.
DR   PATRIC; fig|442562.3.peg.1402; -.
DR   HOGENOM; CLU_031953_0_1_5; -.
DR   OrthoDB; 9767905at2; -.
DR   Proteomes; UP000019666; Unassembled WGS sequence.
DR   GO; GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR   InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR   PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR   PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR   Pfam; PF00180; Iso_dh; 1.
DR   SMART; SM01329; Iso_dh; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR   PROSITE; PS00470; IDH_IMDH; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000313|EMBL:EYD76894.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019666}.
FT   DOMAIN          2..347
FT                   /note="Isopropylmalate dehydrogenase-like"
FT                   /evidence="ECO:0000259|SMART:SM01329"
SQ   SEQUENCE   361 AA;  38782 MW;  1EC847E065552A82 CRC64;
     MRLLVLPGDG IGPEITASTL RVLDAVRVRL SLDVQVESMD IGLASLATQG TTLPEAVMRR
     IPEVDGVILG PVSHYEYPPK DRGGLNPSGE LRTKFELFAN IRPCRSLPDL SILRKPMDLV
     IVRENTEGFY SDRNMFAGSG EFMPDPDMAL SVRKITARAS SRVARAAFDL ARGRRRKVAA
     VHKANVVKLS DGLFLREVRK VAQEFPEVQL EELIVDAAAA HLIRSPDRFD VIVTTNMFGD
     ILSDEASELC GSLGLGGSIN AGDGICVAQA QHGSAPDIAG QGVANPTSLI LSLAMLLEWL
     GQRHGDARLS QGASLVEAAV EETIRNPATR TRDLGGTLGT EGFTEQLCQR LAPTGEPKTA
     P
//