ID A0A022MCK0_9ACTN Unreviewed; 343 AA.
AC A0A022MCK0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:EYT79609.1};
GN ORFNames=CF54_30230 {ECO:0000313|EMBL:EYT79609.1};
OS Streptomyces sp. Tu 6176.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1470557 {ECO:0000313|EMBL:EYT79609.1, ECO:0000313|Proteomes:UP000020060};
RN [1] {ECO:0000313|EMBL:EYT79609.1, ECO:0000313|Proteomes:UP000020060}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tu 6176 {ECO:0000313|EMBL:EYT79609.1,
RC ECO:0000313|Proteomes:UP000020060};
RA Olano C., Cano-Prieto C., Mendez C., Salas J.A.;
RT "Draft genome sequence of Streptomyces sp. Tu 6176, producer of the
RT cytotoxic benzoxazol nataxazol.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYT79609.1}.
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DR EMBL; JFJQ01000954; EYT79609.1; -; Genomic_DNA.
DR RefSeq; WP_018566186.1; NZ_KK106992.1.
DR AlphaFoldDB; A0A022MCK0; -.
DR HOGENOM; CLU_037628_6_1_11; -.
DR OrthoDB; 2854648at2; -.
DR Proteomes; UP000020060; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..57
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 343 AA; 36952 MW; 0CEF517A5E9BB17C CRC64;
MRVSLKDVAS HAGVSIKTVS NVVNDHPHVS PAMRARVQKS IDELGYRPNL TARHLRKGRT
GIVALALPEL GNPYFAELAA EVVDAAAAHD YTVLLDHTGG RRDQEALVSQ GFRARVIDGL
ILSPIELEAE DLRARAEPVP LVLLGEREYD LPHDHIAIDN VAAAREAVRH LISLGRRDIA
FLGARRGRSQ PAHLRLRGWR EALDAAGLVA DHRLVAATDG WGHADGAAAM ARLLDAGHRP
DAVFAYNDPI AIGAMRVLAE RGLRIPEDVA VVGFDDVVEG RFGAVTLTSV SPDKASIARM
AVESVLSQLD GAPRKEGRRI HAGHRLVRRE STLGFDAPPP APA
//
