ID A0A022QH27_ERYGU Unreviewed; 308 AA.
AC A0A022QH27;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=6-phosphogluconate dehydrogenase NADP-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MIMGU_mgv1a024488mg {ECO:0000313|EMBL:EYU26538.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU26538.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU26538.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
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DR EMBL; KI631651; EYU26538.1; -; Genomic_DNA.
DR RefSeq; XP_012850181.1; XM_012994727.1.
DR AlphaFoldDB; A0A022QH27; -.
DR STRING; 4155.A0A022QH27; -.
DR GeneID; 105969956; -.
DR KEGG; egt:105969956; -.
DR eggNOG; KOG0409; Eukaryota.
DR OMA; METPYPK; -.
DR OrthoDB; 203032at2759; -.
DR PhylomeDB; A0A022QH27; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF13; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 2, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748}.
FT DOMAIN 15..169
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 174..298
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 180
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 308 AA; 31712 MW; 0C09E3E134495BDA CRC64;
MSSRYPAPIT LTRTRIGWIG IGVMGGAMAS RLIAAGYSLS VYARTPSKAT SLLSLGATLA
HSAADLAASC DIIFTMIGHP SDVQTLILDT LIPAITPGTV IVDHTSSHPA LARRIHLSAL
ESRCHSVDAP VSGGDVGARS GKLAIFAGGD ADVVQWLKPL FDVLGQATYM GSAGKGQSCK
IANQITVGGN LVGLSEGLVF AEKAGLDKVK FLAAVSGGAA GSAAMELFGK RMIDRDFRPG
GFAEYMVKDL GMGVDVVLEE EEAAAVVVLP GAALSKQLFS GMVANGDGKY GTQGVITVIE
RINGVNHD
//
