ID A0A022R0Y2_ERYGU Unreviewed; 806 AA.
AC A0A022R0Y2;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=MIMGU_mgv1a001505mg {ECO:0000313|EMBL:EYU33253.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU33253.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU33253.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX21/DDX50
CC subfamily. {ECO:0000256|ARBA:ARBA00006517}.
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DR EMBL; KI630784; EYU33253.1; -; Genomic_DNA.
DR RefSeq; XP_012842389.1; XM_012986935.1.
DR AlphaFoldDB; A0A022R0Y2; -.
DR STRING; 4155.A0A022R0Y2; -.
DR GeneID; 105962620; -.
DR KEGG; egt:105962620; -.
DR eggNOG; KOG0331; Eukaryota.
DR OMA; IQYFIPA; -.
DR OrthoDB; 1188at2759; -.
DR PhylomeDB; A0A022R0Y2; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000373; P:Group II intron splicing; IBA:GO_Central.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd12938; GUCT_Hera; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR012562; GUCT.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08152; GUCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 148..324
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 353..498
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 787..802
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT REGION 638..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..772
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 806 AA; 86477 MW; A4BAEDCC6465C456 CRC64;
MASSLIGVSS VYQTNPAADH PKPSNSAAPL SFHFSTAHNP FRYFSSSSAA RLKSASKSLV
TSAVFAPNSS VLSEEAFKGL GGFRKGQLDV SGAEYDDGVG SAEGGFGGIA AANVDELDVS
KLGLPQRLVD TLAKRGITQL FPIQRSVLVP ALEGRDIIAR AKTGTGKTLA FGIPILKGLD
AENERGSLRR GRFPKVLVLA PTRELAKQVE KEFTESAPYL STVCIYGGVS YVTQQSALTR
GVDVVVGTPG RIIDLINNNN LQLGEVQYLV LDEADQMLAV GFEEDVETIM EKLPPVRQSM
LFSATMPSWV KKLARRFMNN PLTIDLVGDQ DEKLAEGIKL YAIPTTTTSK RSILGDLVTV
YAKGGKAIVF TQTKRDADEV SLALTNSIPS EALHGDISQH QRERTLNAFR QGRFTVLVAT
DVAARGLDIP NVDLIIHYEL PNDPETFVHR SGRTGRAGKE GRAVLMFTSS QRRTVKSLER
DVGCRFEFIS PPSVQEVLEA SADQVVATLG GVHPESIQYF TPTAQRLMDE RGVDALAAAI
ATLSGFSQPP SSRSLITHEQ GLVTLQLTRD SVYSRGALSA RSVTGLLSDV YSAAAGEVGR
IHIIADEQVQ GAVFDLPEEI AKELLNKELP PGNTIAKISK LPTLQDDGPA SDYYGRFSNN
ERRPQRGSTD RRSSFKSSGD WLDGNDDDEG GYKRGGGGGG RGRGGENRWS KNSRSSGSSD
WLISDRKTSR SPSYGGGRSP SYGGGRSSSY GGGGRSSSFG DRDRSPSYGG GRSSSFGDKD
RSFGGACFVC GRSGHRASEC PNKKEY
//
