ID A0A022RBR4_ERYGU Unreviewed; 753 AA.
AC A0A022RBR4;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Peptidase S8/S53 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MIMGU_mgv1a001832mg {ECO:0000313|EMBL:EYU37178.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU37178.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU37178.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; KI630559; EYU37178.1; -; Genomic_DNA.
DR RefSeq; XP_012837786.1; XM_012982332.1.
DR AlphaFoldDB; A0A022RBR4; -.
DR STRING; 4155.A0A022RBR4; -.
DR GeneID; 105958324; -.
DR KEGG; egt:105958324; -.
DR OMA; WFSHETP; -.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795:SF463; OS12G0427600 PROTEIN; 1.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..753
FT /note="Peptidase S8/S53 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001504973"
FT DOMAIN 27..118
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 141..572
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 391..452
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 652..749
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT ACT_SITE 150
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 208
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 536
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 753 AA; 80159 MW; 659E1FE6B33E852E CRC64;
MATMFLLAAI FIFTFHSASS SNTSYQTYIV HVDLPPTEED GFSGQSNLET WYHSFLPPSS
EAATSDSDNH YTPSSRIVHM YRNVITGFAA KLSPEEVKEM EKKPGFMHAR PHKKYQLHTT
HSPNFLGLHQ GVGAWPASNY GNGVIIGVID TGITPGHPSF NDQGMPPPPP KWKGKCELSG
TLSCNNKLIG ARNFASYFPG PPIDNFGHGT HTASTAAGNF VSGANVFGQA NGTASGIAPL
AHLAIYKVGS HENGTDVLFD SDLLAGMDAA IEDGVDVLSL SLAGDSVSHT SPFHEDVVAI
GAFSAVKRGI FVTCSAGNDG PSHSSLYNTA PWILTVGAST TDRKIKATAL LGNGEAYEGE
SFYQPEEGGS SSEELLPLVY GALCGSELLG EIGVKGKVVL CEIGTFNNGQ DVKDAGGAAM
IGINDETDDY YTEPIPHVLP ATLVNYEAAL KIKAYIEDAN SSTPTSAILF GGTVIGDKTA
PMVTPFSSRG PNLVSPGIIK PDIIGPGANI LAAWPVSIDN NIKEKTATYN MVSGTSMSCP
HLSGVAALVK SAHPDWSPAM VKSAIMTSST QTNLGNIPIL DQRHQPADVF AVGAGHVNPP
AALNPGLVYD ISARDYISYL CFLYTERQVA AIVNRKIDCS SKSEYSGVPE AQLNYPSFSV
VLGQDIGYAY SRTVTNVGEA ESTYYAKIEC FPGVSIFVEP TVLSFTEVKQ QLTYEVYFSR
TEFTTNGSYV QGSISWVSTK HVVRIPVSVK LVL
//
