ID A0A022RM28_ERYGU Unreviewed; 575 AA.
AC A0A022RM28;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=1-phosphatidylinositol 4-kinase {ECO:0000256|ARBA:ARBA00012169};
DE EC=2.7.1.67 {ECO:0000256|ARBA:ARBA00012169};
GN ORFNames=MIMGU_mgv1a003591mg {ECO:0000313|EMBL:EYU40010.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU40010.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU40010.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type II PI4K
CC subfamily. {ECO:0000256|ARBA:ARBA00008941}.
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DR EMBL; KI630433; EYU40010.1; -; Genomic_DNA.
DR RefSeq; XP_012834259.1; XM_012978805.1.
DR AlphaFoldDB; A0A022RM28; -.
DR STRING; 4155.A0A022RM28; -.
DR GeneID; 105955108; -.
DR KEGG; egt:105955108; -.
DR eggNOG; KOG0001; Eukaryota.
DR eggNOG; KOG2381; Eukaryota.
DR OMA; SDMIFIV; -.
DR OrthoDB; 1699at2759; -.
DR PhylomeDB; A0A022RM28; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:UniProtKB-EC.
DR CDD; cd17039; Ubl_ubiquitin_like; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR044571; P4KG1-8.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45800; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA; 1.
DR PANTHER; PTHR45800:SF5; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA 2; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF00240; ubiquitin; 1.
DR SMART; SM00213; UBQ; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030748}.
FT DOMAIN 29..102
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT DOMAIN 107..187
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT DOMAIN 255..556
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
SQ SEQUENCE 575 AA; 64010 MW; 83C77F775E65CEFA CRC64;
MPAVDVALSP IHKETNRDSS SVHLNRRLES IVIYITVGGS SIPMRVMESD SIASVKLRIQ
SCKGFVVKKQ KLVFGGKELS RTDSLVKDYG ITNGNVLHLA LRISDVLLIN VSTVCGKQFE
LQVDRHRNVG YLKRRIIKKG KGKGFIDLEE PVIFCHGEKL EEDQRLINDI SKDNDAVIHL
VVQKSAKVWT KPVEKDVELS IVAPHSDRCT DISVLSRAPL VEDFFLKPII VNPNVNLPPF
LWDMIDSVFE GLANGKQPIR SSEGTGGTYF MQDSTGEKYV SVFKPVDEEP LAVNNPQGLP
LSTSGEGLKR GTRVGEGALR EVAAYLLDHP KTGPRSKSDS QIGFAGVPPT IMVRCLHGGF
HHPEGFDRSN ENIKTGSMQM YMKNNGSCED VGPGVFPVEE VHKISVFDIR TANADRHAGN
ILLRKKDGEK NGNNIVLIPI DHGYCLPENF EDCTFEWLYW PQTREPFSQE TKDYIKSLDA
EQDLAILDFH GLNISHECAL TLRISTMLLK KGAERGFTPF VIGSIMCRET LNKKSVIEEI
VDEAKEYSVI SGMTEAAFLE TVSEIMDETL DKLMK
//
