ID   A0A023B8Y8_GRENI        Unreviewed;      1498 AA.
AC   A0A023B8Y8;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:EZG70692.1};
GN   ORFNames=GNI_054450 {ECO:0000313|EMBL:EZG70692.1};
OS   Gregarina niphandrodes (Septate eugregarine).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Gregarinasina;
OC   Eugregarinorida; Gregarinidae; Gregarina.
OX   NCBI_TaxID=110365 {ECO:0000313|EMBL:EZG70692.1, ECO:0000313|Proteomes:UP000019763};
RN   [1] {ECO:0000313|EMBL:EZG70692.1, ECO:0000313|Proteomes:UP000019763}
RP   NUCLEOTIDE SEQUENCE.
RA   Omoto C.K., Sibley D., Venepally P., Hadjithomas M., Karamycheva S.,
RA   Brunk B., Roos D., Caler E., Lorenzi H.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EZG70692.1}.
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DR   EMBL; AFNH02000416; EZG70692.1; -; Genomic_DNA.
DR   RefSeq; XP_011129875.1; XM_011131573.1.
DR   EnsemblProtists; EZG70692; EZG70692; GNI_054450.
DR   GeneID; 22911997; -.
DR   VEuPathDB; CryptoDB:GNI_054450; -.
DR   eggNOG; ENOG502QPPT; Eukaryota.
DR   OrthoDB; 3076794at2759; -.
DR   Proteomes; UP000019763; Unassembled WGS sequence.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 2.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 2.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR47455; ADENYLYL CYCLASE BETA; 1.
DR   PANTHER; PTHR47455:SF1; GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00211; Guanylate_cyc; 2.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019763}.
FT   DOMAIN          54..200
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   DOMAIN          295..417
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          675..709
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          970..1033
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1151..1203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1359..1384
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1414..1441
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1456..1498
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        695..709
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        994..1023
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1172..1195
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1359..1377
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1420..1441
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1469..1498
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1498 AA;  162783 MW;  FE75944859458443 CRC64;
     MGNAGRSAPV AVVEVSEIDR FSCFVPRAVL EGIVDEKIRL ADDFDIVVDR CSGALVFCDA
     SGFTAVTEAF NKQPNGAERL GNVINDFFTS LIQIINFWGG DIIKFAGDAV TIVWGVDDSL
     SDSMSTYKID PVTACKLACQ CCLDLHRNLN GFPAGIEDRV FTLHIGVGYG PITILQVGGT
     LDRWDFVVAG PPVTQISIAE PLASSGDTVL SPEVVATLRS SADGGGVITE EVPDSGQHHK
     LVSLAGEATA APPPLEKIRL EHSCILLLKR FIPPPIYKRL NAGFNAFSNE LRQLSVIFVS
     VKGLDVDTHV GSIKANSLMQ YCQKSAYLLE GSVNKFSVDD KGVVVLLMFG LPPVYHMDDP
     IRAVLCSLRI GEGLKTLGLA CGIGVATGRV WVGTVGCDIR KEYTALGDTV NLAARLMGKA
     KVDEVLCDQT THLLCSHAIE FEELAPVKMK GKADLVPMFR PPGRLKKFDE QKSLDPAVAY
     WPGWRQTSVL RRLFFPPVRF RPFVANFDLP LPVLDYNGYG PCYPWEIKEP WLPTLRNAMD
     LGGVMVIQGR EVQGSLELVE YLKDLAEASG HQVFICSNTP EASYLPVANV PLLAFRKLCT
     DVVFRWKKSQ IRKQKGYTAV DEKNSIYSLT KELTHPLFHW RLTAMKAVVK GLVLPRELPR
     NQPVEKWNHR TSYLVATDGP AGGSGPGPGS VSAGSDKGDR SSSVATTGGT SKLLSSLKNL
     VQHSRGSWNK AASVTPDVER SSKEEELVSV EDAFGVHSSV VVPAICSLIN GYTMNERTVI
     IVRVRQGTSL YSSMDGDSWK TLALLANMAA LRRRRRVELE CQNLRRWRRR HSWSCPWCKG
     VSQRSNGEAA KAKWTSRCRP PATVYFPPFL LVVVCSQNNV RESSRLCAWA RECGLFMNLG
     KLSRSETRSF LSYYYKTSKK KIPGEVVDYV HRVSAGYLNY VALTARQLLH HDAIEAVPVV
     SHTRLGAGVT TSATTTGGGT TRPGGGITGP GGGTKGTGGS TTGTGGGTMG TGGSTTGTGT
     GTSEEKPPPR ADSQVYVSGA ATSAQFHGEE SVATTSEEDL ADYDTVQERK VARDAALTER
     ERRIVIRRRR VLPTCCGVLV GFKFEGNDVA QLRGCVVERD VTFQGNIITG MGHWIRRGPG
     LLPGTNGVRA GGGPGAGLGG IRQISEGGGR VTEEGDGTER DDDRGETRGE GIEGVRGMDG
     RNVPNHFGCP GPVEYAEKEG SLTLHSRMTE RIFGVPFPED NDRLVRLIEP SSKQKRLVVT
     RDLRSVPYIA QLRAATMMLI EALEPEEQLV AKCASVFTLP FCFYELSAIF PKAITLRRLE
     AIVESLLRRE LLEICDPPTD AELEELDLYS VLKAFARHPR DDPSSTIRTD DELGSSVKDS
     TTSEGDLINE AHLAEEALLR HASLYRRSAV VVAPTGRPTE DPAPTSNLAS ANGTSRPSDT
     TALGVLRFDD NIIRPKDKDI HTFNKRDVQG SRRPSGPTPN PLAPADSNSI KNTTSAFK
//