ID A0A023BPR4_9FLAO Unreviewed; 3516 AA.
AC A0A023BPR4;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Carrier domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ATO12_04990 {ECO:0000313|EMBL:EZH71976.1};
OS Aquimarina atlantica.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Aquimarina.
OX NCBI_TaxID=1317122 {ECO:0000313|EMBL:EZH71976.1, ECO:0000313|Proteomes:UP000023541};
RN [1] {ECO:0000313|EMBL:EZH71976.1, ECO:0000313|Proteomes:UP000023541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=22II-S11-z7 {ECO:0000313|EMBL:EZH71976.1,
RC ECO:0000313|Proteomes:UP000023541};
RA Lai Q.;
RT "Aquimarina sp. 22II-S11-z7 Genome Sequencing.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EZH71976.1}.
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DR EMBL; AQRA01000010; EZH71976.1; -; Genomic_DNA.
DR RefSeq; WP_034246254.1; NZ_AQRA01000010.1.
DR STRING; 1317122.ATO12_04990; -.
DR eggNOG; COG2898; Bacteria.
DR eggNOG; COG3321; Bacteria.
DR OrthoDB; 1230081at2; -.
DR Proteomes; UP000023541; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd08953; KR_2_SDR_x; 1.
DR CDD; cd00833; PKS; 2.
DR Gene3D; 1.10.1240.100; -; 2.
DR Gene3D; 3.40.47.10; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 2.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR049490; C883_1060-like_KR_N.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR024320; LPG_synthase_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF21394; Beta-ketacyl_N; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 2.
DR Pfam; PF00109; ketoacyl-synt; 2.
DR Pfam; PF02801; Ketoacyl-synt_C; 2.
DR Pfam; PF08659; KR; 1.
DR Pfam; PF09924; LPG_synthase_C; 1.
DR Pfam; PF21089; PKS_DH_N; 2.
DR Pfam; PF00550; PP-binding; 2.
DR Pfam; PF14765; PS-DH; 2.
DR SMART; SM00826; PKS_DH; 2.
DR SMART; SM00822; PKS_KR; 1.
DR SMART; SM00825; PKS_KS; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00606; KS3_1; 2.
DR PROSITE; PS52004; KS3_2; 2.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000023541};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 9..82
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1000..1425
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 2423..2497
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2568..3005
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT REGION 490..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 958..980
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2500..2533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 490..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2519..2533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3516 AA; 396164 MW; 067731AAD425B10E CRC64;
MIDKEILLES TESYLKSLIS QFSQVPIGDN CVSTPFQELG IDSFRILQII KKLEEEFGTL
PKTLLFENFN IGDLSYYFVD KHEGILREKF KQEKEGNDRA VYSNEESSNS TEEITEIFDN
RYDVNKEETP VLILEKEANK HPELLKLVEK LFNQYKNEGS ASRGTRNIAP NLFIGAEKKG
YFNYSRYKDI ILVYSYTGAK DYLSVITEEI YQYCINNNFE LNLFTVDQVE SIRGVLFTAT
PFGVLSRVNI KDFTLQGSKM RRLRYQVSKF ERAGKCRIEE YQNGSDKKVD KNITQIIDEW
CAPRTMVNPL IHIVKEEILS GNLSAEHRLF LTYLDDVLQN VILISKLSSE ENGYLMDLEF
YPKSMPLGGL EYAIVEIIKT LKAEEYTTLS LGGTYGCKLN SSSNADPELD KTLDYLRGQN
IFNDEGNLQF KNKFRPEHNT VFLSRPVGSN PDNVTDIIMM IADPMKMQTS DEENHTFTKL
DKQTVALESK TARQNTSNSN GEFKQVKENP QVEKHKVVIE GEERSIMLSD YGYNPLNIPG
DQVTFDLKTD SWAQLELPVI QNQLSFLYTQ LQQPVDLVES LKNIFPFSYF TLTTAGRTAE
RAFCKSWPKK GKVLQNLLFP TMIFNQIENG FTPIELPHPG VYKLDAEDQY KGNLNWEALK
KQVEEDPESI AFVFIEMNDN AAGGAPVSLQ HLKQVKTFLS EYAIPLVFDT TRIVENALFI
LEHENEFIGK NVWDVVREMV SYADAIIASL AKNFCVDKGG LIGTNDVELY NKIQNFIQEE
SIGLDVIDKK VIGLSFHNRN KIEAWVRNRL QSVQTIWRVL KQQGIPVVQP ALGHCILIDV
KQIPEFELFE YPVASFVSWL YLNTGIRAGA HNVGMQKDTE INNLVRLAIP VGLKQEKIEE
IANRLIKAFQ KKTNIPEILP KDNQSETFGN IHTNFNLKKY HNTSGKVVSK TLNSETSSID
NDNNFSITES TGKSTQTDSD IKVKETGANQ NIQNDKPYQT GDIAIVGIAG RYPKAKNMNE
FWNNLVQGKD CVEDIPDVRF GQRLHNKFSE KYRGGFIDDI DKFDSLFFNI SPREAEYLDP
QERLFLEVAW EAIEDAGYYP ETLVDDNASR NIGVYVGAVW TLYQVIGTEE KLQGNFVSPS
SHLWGIANRV SYAFNLSGPS LPIDTACSSS LSALYLACEA IYKGECSGAI VGGVNLDAHQ
SKIDINKSGG ALSADGVCRT FGKGANGYVA GEGVGAVYIK PLDKAIKDGD HVYGVIKGIA
VNHGGKTSGF MVPSPKSQAQ VVTTALESGK IDARSIGYVE AHGTGTELGD PIEISGLTAA
FQEYNVDKQE CSIGSVKTNI GHLEAAAGIV GLHKVLLQMK YKKLVPSLHS SELNPFIDFK
NSPFYVEQTV KEWKPKTIEG VQYPLRAGIS SFGAGGANAH VIIEEYVTPI EEEKTPSSKF
KEYIFPLSAR NENQLRETAI RLSTYLQDDL SGEKLLTCKD IAHTLQIGRK SFDHRLVIIA
KTKQELVQKL TLFIDGKQDN AMLTGEVKNS QNITRLLNRK EKEEFIKFLS QSGDLSKLAQ
LWSVGFLADW QGIQALEAGA KISLPTYPFA DKRHWISDTS KSSNLSLHST TALHPLIDSN
ESTFERQVFK KTFHDKDFFI YDHLVSEIPT LPGVAYLDFA RKAGELATGR KVQIIKNILW
LSPLTVVDSV PKEVCIELKP NGGLVHFEVF SEEENNTKQI YSQGKLIYAT HEELTAEPEY
IDLEEIRTRC VKVTDGKEAY PLFKSLGLDL GPSFQVLQDI FKNDDEILGE LLIPEIRNND
FNDYLLHPSL VDGSFQAGMA AQLGEQTGEM FVPYSIGEVE VLQPLKPKCF SYVKKVDEPG
SKVSKVNVFI VDEDGMILVK IRESIGVPLV SVHEKPDQTK EEEEYSKLYY SHEWKKSLLE
QEKVLSNESG PILLFSPDEK LQKVYKDRYK KNEDIILIEP GDKFKKLGSH KYKINPQNPA
DFKKLFEALN KDIIKNICFA WPIGDELKDD DEYEEGFIQK SFDNGIYSFL MLCQSLIEQK
LDNVQLLYLY LGQIGTSQPH HEAINGFAKT LQMEHPKLYC KILEIQQSKK SYDKILDIVL
TELHSDNSNE MTIRYQEEER YVRKVKEFSL LQDQDSDRTD SFGLKEKGVY IITGGAGGLG
LIFAEYLAAQ CKARLVLTGR SKLSGERQTK LDRLSEVGAE VMYIPADVSI AKDVENLVKK
AKSKFGKING IIHSAGVLRD SYVRSKTREE MEAVFAPKVY GTLYLDRITK DEDLDFFVTF
SSLAAVGGNA GQCDYSFANH FMDSFAEKRK LLQEKGERSG VTLSLNWSLW ADGGMKLDEQ
TEIFFKKNLG IKPLSIKTGL EAFEKGLHTR KAQFVVLEGV QEKIERAWGI KEKETPEAVA
TDSKTSTDSE VQVDQQADKE LFIVVRDALS KIVMEMLKLD PEDISYDKIL LDLGFDSIGL
TTYANRINEL YELDITPVLF FEYPSIKEIA TFLSREHKNE VQKTHEVSGG TSTSDIKKEA
SQPAKRKEEY SDAEKGILSI NKGWNASALD QQSQSPGEAL STESRFIDQP IAIVGMSGVM
PGSENLEEFW ENLENEKNLI TVIPEDRWNW EDYDGDPFRE KNKTNSKWGG FMSDVDKFDP
SFFGISPREA EMMDPQQRIF LETVWKAIED SGHKVSDLSG TKTGLFVGVA TRDYADSLVD
NQIPLDGYTA SGNSHSVLVN RVSFLLNLRG PSAPLDTACS SSLIAVHRAI ESIHTGSSDM
AIVGGVQLML TPAAYISFGM AGMLSGDGKC KTFDKSANGY VRGEGSGAIF LKPLDKAEAD
RDHIYAVIKA TTENHGGKVT MLTAPNPVAQ TDLLVEAYQK AHIDPSTVGY IECHGTGTSL
GDPIEIQALN KTFSELYKKH NKAPAKTPHC GLSSVKTNIG HLETAAGIAG VLKVLLSLKH
KKIPATLHFE ELNPYINLKD SPLYIVDKTQ NWEVIKDDQD NTLPRRAGVS SFGFGGANSH
IVLEEYIQEE DHSQIQLDEP HIIVLSAKTE DRLKAYTQLL YNHVEKHDIN LTNLAFTLQV
GRDEMDERLG LVVNSIEELK EKLSDYLSQK ENIEDIFYDR VKQNSAAVID STEKNDFSET
QIDKYINDKN YSRLTEAWVM GIHIDWAQLY KQVKPRRISL PTYPFARERY WFNLVDSEKL
KSAGEFEKLH PLLHYNSSTL SQQCYTSTFS GKEFFIKDHK IQQQNVMPFT ACLEMAYVAV
KNAMPDLNES TTLELRNTFC VNLLTIKDNK EVNISLVENN DKGVDYEIYS IEGEKEIIHC
EGEVVILANQ NSTNIDIVQL KTHFTTQAIN PEELYQVLKQ MDMSYGPSFK GIKNFYKGED
QILAQLSLPE TITDDYKNYA LHPSLIESSL QLAIGLLTDL DSKLNQPILP FEIGSVKLFS
PCQKELYAWV RYSKGSKQED DIVNVDIDLT DKSGEVCVKM KSLAFDSTLY KQTKKNTYKD
FEMLINAIHN GDTREQEYAE TENSETSFNQ LLKDLY
//
