ID A0A024FXY4_9STRA Unreviewed; 792 AA.
AC A0A024FXY4;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BN9_002070 {ECO:0000313|EMBL:CCI39424.1};
OS Albugo candida.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Albuginales; Albuginaceae; Albugo.
OX NCBI_TaxID=65357 {ECO:0000313|EMBL:CCI39424.1, ECO:0000313|Proteomes:UP000053237};
RN [1] {ECO:0000313|EMBL:CCI39424.1, ECO:0000313|Proteomes:UP000053237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ac Nc2 {ECO:0000313|EMBL:CCI39424.1,
RC ECO:0000313|Proteomes:UP000053237};
RA Gardiner A., Kemen E., Schultz-Larsen T., MacLean D., Van Oosterhout C.,
RA Jones J.D.G.;
RT "Recombination and specialization in a pathogen metapopulation.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI39424.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAIX01000001; CCI39424.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A024FXY4; -.
DR InParanoid; A0A024FXY4; -.
DR OrthoDB; 54187at2759; -.
DR Proteomes; UP000053237; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR PANTHER; PTHR13018:SF98; TO DEHYDRATION PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053237};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 519..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 684..705
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 712..734
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..168
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 187..300
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 426..703
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 332..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 792 AA; 89771 MW; 8CC8468D064BC0A1 CRC64;
MSATDENVED LTPSRTLVNG IRIYFSVALV GWLAFEIARK RMLRTYYCRD YSAEWKHSLI
GSLQQQRWFT WLYSLYMVKD DWILMNCGMD ALFYLRFLRM CQKIAMCGMF LSGMLFPLYH
YAASDSADTL YKLTLSHLVS TSGEWRFWFP LLALVAMSFF TLYLLGKEYE QYVIRRHEFL
GRQALQQYSV VITGLPSYLR QPQVLRKYMD DLFPDSVLHV YIAVECSHLE LLVRERTRIC
NQLEHSLALS AHKSDRVLLP LKVSRCWKGD TTSVDAIDHY QSRLDTLNTA VLNEARRISK
FEDSGPTQDF QIGPITSAVE VLAFTENNEY QALHSPSDND SKLKRKEKSG ISTEMLHDDS
SASNPVDGML GCAFVTFNNL RATQAAQQVL QCADPTHMIV EEAPPLEEVL WQNVGVSHTQ
KLTFFMISFT LTCGIILFWT IPTSLVVSLA NVDQLQKKWK WLRDVVADNH WISAVLEQVA
PLVMVIMSSM APMIFGILSK REGHASESKV NSSLFNKLVS YQSFVTFLLP LIVDSLVQSI
TTFAKDFGAL VNTLSGTIPV KSSYYMSYVI IQLGLNMTLE LLRVVPIVKG TIYDMFAPKL
TAKQRESAWF GLQPVHRPGP YEICGPLSEV FLVLILILVF APIAPMMCYV CLLYFSLSEL
INRWSFICVF DPRPHSSADF FPSVYRFCIG AVLLSQFVMA GLLALKKVPA PAAVALLLPI
ATIAYHMFIA SRYVRPAKNL PLDKCTLVDA RRARKMEMLT SVLEESYKQP ALAECGPVKP
DYSNLGSECN NV
//
