ID A0A024HMP8_PSEKB Unreviewed; 529 AA.
AC A0A024HMP8;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=pilS {ECO:0000313|EMBL:CDF86106.1};
GN ORFNames=PKB_4786 {ECO:0000313|EMBL:CDF86106.1};
OS Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1301098 {ECO:0000313|EMBL:CDF86106.1, ECO:0000313|Proteomes:UP000025241};
RN [1] {ECO:0000313|EMBL:CDF86106.1, ECO:0000313|Proteomes:UP000025241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B13 {ECO:0000313|EMBL:CDF86106.1,
RC ECO:0000313|Proteomes:UP000025241};
RA Linke B.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDF86106.1, ECO:0000313|Proteomes:UP000025241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B13 {ECO:0000313|EMBL:CDF86106.1,
RC ECO:0000313|Proteomes:UP000025241};
RA Miyazaki R., Bertelli C., Falquet L., Robinson-Rechavi M., Gharib W.,
RA Roy S., Van der Meer J.R.;
RT "Genome sequence of the 3-chlorobenzoate degrading bacterium Pseudomonas
RT knackmussii B13 shows multiple evidence for horizontal gene transfer.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; HG322950; CDF86106.1; -; Genomic_DNA.
DR RefSeq; WP_043255029.1; NZ_HG322950.1.
DR AlphaFoldDB; A0A024HMP8; -.
DR STRING; 1301098.PKB_4786; -.
DR KEGG; pkc:PKB_4786; -.
DR PATRIC; fig|1301098.3.peg.4774; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_114_39_6; -.
DR OrthoDB; 9815750at2; -.
DR Proteomes; UP000025241; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065:SF52; SENSOR PROTEIN KINASE PILS; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000025241};
KW Transferase {ECO:0000313|EMBL:CDF86106.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 315..526
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 529 AA; 58391 MW; 5BD3CA51E0A0C983 CRC64;
MAKAIPLSGQ QGQRILRLYH LYRLSIGLAL VLLISSNLDN HILAPRDIEL FHIGCWGYLI
INILIAVLMP SPRQLLPIFC IALLDIILLC GLFFAAGGVP SGVGNLLVVA VAIANILLRG
RIGLLIAAVA AIGMIYLTFY LSLSQPSAVN HYLQVGGLGA LCFAAALLLQ GLTRRQQLSD
SLAEERATTV ANLQELNAQI LQRMRTGILV LDSQQRILLA NQSAHSLLAE SELAARRLAT
YSQDLLDSLQ QWSQNPSLRP PSIQAPDSGP TLQPSFIPLR HGEEQHTLVF LEDISQIAQQ
AQQLKLAALG RLTAGIAHEI RNPLGAISHA AQLLLESEAL DAPDRRLTQI IQDQSRRMNL
VIENVLQLSR RRQAEPQLLD LKYWLQRFSA ELCESLRPDQ QIHVQMGDGS IQTRMDPNQL
TQVLGNLVQN GLRYSAKQHG KGQVWLNLFR DSESDLPVLE VLDDGPGIAE EQLGKLFEPF
FTTESKGTGL GLYISRELCE SNQARIDFKN RDEGGGCFRI TFAHPLKQS
//
