ID A0A024U154_9STRA Unreviewed; 725 AA.
AC A0A024U154;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:ETV99337.1};
GN ORFNames=H310_08062 {ECO:0000313|EMBL:ETV99337.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETV99337.1};
RN [1] {ECO:0000313|EMBL:ETV99337.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETV99337.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI913967; ETV99337.1; -; Genomic_DNA.
DR RefSeq; XP_008871893.1; XM_008873671.1.
DR AlphaFoldDB; A0A024U154; -.
DR STRING; 157072.A0A024U154; -.
DR EnsemblFungi; H310_08062-t26_2; H310_08062-t26_2-p1; H310_08062.
DR EnsemblProtists; ETV99337; ETV99337; H310_08062.
DR GeneID; 20085112; -.
DR VEuPathDB; FungiDB:H310_08062; -.
DR eggNOG; KOG0585; Eukaryota.
DR eggNOG; KOG2243; Eukaryota.
DR OrthoDB; 53282at2759; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14008; STKc_LKB1_CaMKK; 1.
DR Gene3D; 1.10.490.160; -; 1.
DR Gene3D; 6.20.350.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR003032; Ryanodine_rcpt.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24346:SF77; CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 1; 1.
DR PANTHER; PTHR24346; MAP/MICROTUBULE AFFINITY-REGULATING KINASE; 1.
DR Pfam; PF00069; Pkinase; 2.
DR Pfam; PF02026; RyR; 2.
DR SMART; SM00233; PH; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000313|EMBL:ETV99337.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:ETV99337.1};
KW Transferase {ECO:0000313|EMBL:ETV99337.1}.
FT DOMAIN 8..105
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 125..446
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 327..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 153
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 725 AA; 80445 MW; 1C733B5E1B7FAA4E CRC64;
MPRFAVVCLV REGLLDYVNS NGKPRSRWFV LDGAQHAMTK YTSPDRSKQL GPPIHILGAR
IERGADLSFT VHLHQRYRSL KRLTYTAHSH DEKEAWMQSL INCINGMASG LAKRMCHRGV
LNGQYIFVRE LGRGASGVVY LYTYHGKPCA VKKLPTKATK FNHHGQLTDA VKREIALLKK
ATNLPHVVSL YDVIQARSGT CRSDSDGEDG NVYLVMEFLG GGPIAAYDKV QKRFTTKQHM
VDADFKRLMR CATIGLKYLH SHHLVHRDIK PDNILMTDDF SECKLADLGV AHWFEPAPTS
VGIQKQDCSI DPRLVNLSSK VCENATALTS TDTVPPPPTP HASDTLDDTK GTYEFLSPEA
ISGDAYSGFA ADVWALGVTL YAVVVGKLPF QADSVLALFD QIAEKPVEFP PTVALSVDVR
DLITRMLVKD PARRMTVDEV LAHPWLCTSS TKSMLMAPAK LVVDDDDVHA AVSPLQAKFD
MMRRASPVDQ MSMLTTVECP GGSAPVSPPA FTTARHRPHP IDIASIALPP VLASELPTLA
QQLHFQWCFD KVLAGWSYGP HRNDDLKLHP LLKPFWELDD GAQTRNRVSV EASLKCILAL
GYTVTRKPNA HQYVPASLAR IALPGELVVL GDLLAENDHE VWATEYVRNG WTHGPMYNPD
TKQHPALVAY TDLPETTRDS TRLGALNIIK SLVSLHYIVQ HRFAKFQPTT LAPPRRFSIM
RRAST
//
