ID   A0A024U3Y1_9STRA        Unreviewed;      1759 AA.
AC   A0A024U3Y1;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   22-FEB-2023, entry version 24.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   ORFNames=H310_06566 {ECO:0000313|EMBL:ETW00905.1};
OS   Aphanomyces invadans.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Aphanomyces.
OX   NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW00905.1};
RN   [1] {ECO:0000313|EMBL:ETW00905.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NJM9701 {ECO:0000313|EMBL:ETW00905.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KI913963; ETW00905.1; -; Genomic_DNA.
DR   RefSeq; XP_008869903.1; XM_008871681.1.
DR   EnsemblFungi; H310_06566-t26_2; H310_06566-t26_2-p1; H310_06566.
DR   EnsemblProtists; ETW00905; ETW00905; H310_06566.
DR   GeneID; 20083616; -.
DR   VEuPathDB; FungiDB:H310_06566; -.
DR   OrthoDB; 37271at2759; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039891; VWA8.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR21610; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR   PANTHER; PTHR21610:SF9; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR   Pfam; PF07728; AAA_5; 3.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
FT   DOMAIN          1568..1756
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          1397..1442
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1759 AA;  195287 MW;  16921E10DB860B0B CRC64;
     MLRQSLLRPS QWRVRRAQHF SNVSIGGVTA PQGQVKEAQL VPKGFANRNA DGEPHFTQET
     LEHLRWMLQK DLLGQDMFLI GPPGPARRRL ALQFCEIMQR EVEYVAISQD TTESDLKQRR
     EILGGSAIFA DQAPVRAAIH GRVLILDGLE KAERNVLPTL NNLLENREMA LDDGRFLMQA
     SSYDALLAKG YTAAQLEARN LLRVDPAFRV IALGVPVPPY PGRTLDPPLR SRFQARQISP
     LSPGAQLEIC SSIPDGEKLV SLVEAMHVIE NNQDGTMDRM PHLNPSVVEY CAKMAETFPN
     TTDVPALLGR LFPLHLTSWK AHSETFEKVL RTFFPFKAVQ AKAAPFVLTR STTDGAQTTW
     LQVDKGKVAI ASGALPLHEH VAGFVETSAH HRVVLDMLKD HALGSDMCVL GPKGSGKSAL
     ARLFCAKLGY STELFTLFKD MTARDLFQRR ATDNDGNTTW EESPLLHAAR HGRVAILDGV
     HRLSSDTLST LQRFVQDREV DLVDGTKFAA SVTDVHRGVV KVHPSFRIVA LAEVTAAHPW
     LTSETLTLFP FHAVPTLTRR DVTKVLADLC PTLPKAIAAT LVDFWHEVQL HPDVSLSLRQ
     LLRMARRLDA FPGTASRDLR HLVEDTTMMH FLPNASVMEG LLDKCNIKQA ARQDKLEDIQ
     FVDTPDSLTV GNVVYNIVKS DAPRVELIPQ PRYFPIPKHA IVMRQMLQDI VSGQPHLLLI
     GNQGVGKNKV VDRLLQLMHQ EREYVQLHRD TTVQTLTLVP SMESGKITWE DSPLVRAVKF
     GRTLVVDEAD KAPLEVVCVL KGLIEDGEML LGDGRRIVDP TEVPVDSAND NVIVMHPRFR
     MWVLANRPGY PFLGNNFFSE VGDIFATHVI DNPDPASELT LLQAYAPSVP QDVLKRLCAA
     FSELRGMVEE GTIAYPYSTR EAVAVAKHLE AFPMDGVSQT LENVLAFDAY DPSLRQRLSD
     VFGRHGVPLV SATTRVLPSI AVAPVSPLPT FSVTETWTLG RCGRHEPVRV DTSTLKSRRI
     YVEPPTSRTF SVTPCRLSTF SEEMSSWHVP LWAQQSAVAM AVLPDGSIHV LTKQPLGVHS
     FFGAESSQRL HLYSELEGYG YSKSEAHLMG WSNSLVLHVP AADLLVVMSA KHNVLESRAL
     CRLKPNQDGV FQWKSDTSSI QVLSGLLDDH DLLVRYIPGH NAVQAIEMTS MKAHTMSLPF
     HVERVHLVSN TTWHVHDTHG NVHMLHIKSP HDADVERIQI SSVGKAIPTS KAVHSHSNRF
     THPEAYVQVI QADGRSRKSV LTSPRAAKSN VIQSLGWNDK LANVVATDVL LEVVDLNKSV
     FRHIPKPHDA SAVTALAVLP STENVLSLQR NGQLRVWQVD DAALHADLET WKAMFSYHSM
     QGVRDMLELK YLPHGTSVPK TDSSLPKHGK EDPDNTPHVG GNTWAGGTGG SDTAGLGGRG
     GPYRLDKGHR VHQISQEKKD QVTKEAREKA KAMADAALAE QLRRIDMTNH EFATYQTYFD
     RVGAETSQLR HILKNVEQQS DERGWLKHQS SGEWDDSKLV DGLSGERNVF KKRGKDPFAL
     QIQTQPKKLV FVMDLSGSMY RFNSQDGRLE RMLETSLMLM ESLAEFETKF DYAIMGHSGD
     SPAIPFVSFG SPPKTKKDRL KILEKMVAHS QYCSSGDHTV EAIADSIKHA KAAAGDDESF
     VFVLSDANLN RYGITPQEMS RALMKDSSVS AHAIFIASLA DEATRILKHL PQGNGHVCLN
     TTDLPHVFQR IFKSNVTKE
//