ID A0A024UB64_9STRA Unreviewed; 575 AA.
AC A0A024UB64;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Dihydroxyacetone kinase {ECO:0000313|EMBL:ETW03509.1};
GN ORFNames=H310_04953 {ECO:0000313|EMBL:ETW03509.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW03509.1};
RN [1] {ECO:0000313|EMBL:ETW03509.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETW03509.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI913959; ETW03509.1; -; Genomic_DNA.
DR RefSeq; XP_008867738.1; XM_008869516.1.
DR AlphaFoldDB; A0A024UB64; -.
DR STRING; 157072.A0A024UB64; -.
DR EnsemblFungi; H310_04953-t26_1; H310_04953-t26_1-p1; H310_04953.
DR EnsemblProtists; ETW03509; ETW03509; H310_04953.
DR GeneID; 20082003; -.
DR VEuPathDB; FungiDB:H310_04953; -.
DR eggNOG; KOG2426; Eukaryota.
DR OrthoDB; 6043at2759; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004371; F:glycerone kinase activity; IEA:InterPro.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.340; -; 1.
DR InterPro; IPR012734; DhaK_ATP.
DR InterPro; IPR004006; DhaK_dom.
DR InterPro; IPR004007; DhaL_dom.
DR InterPro; IPR036117; DhaL_dom_sf.
DR NCBIfam; TIGR02361; dak_ATP; 1.
DR PANTHER; PTHR28629; TRIOKINASE/FMN CYCLASE; 1.
DR PANTHER; PTHR28629:SF4; TRIOKINASE_FMN CYCLASE; 1.
DR Pfam; PF02733; Dak1; 1.
DR Pfam; PF02734; Dak2; 1.
DR SMART; SM01120; Dak2; 1.
DR SUPFAM; SSF82549; DAK1/DegV-like; 1.
DR SUPFAM; SSF101473; DhaL-like; 1.
DR PROSITE; PS51481; DHAK; 1.
DR PROSITE; PS51480; DHAL; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ETW03509.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 10..332
FT /note="DhaK"
FT /evidence="ECO:0000259|PROSITE:PS51481"
FT DOMAIN 366..572
FT /note="DhaL"
FT /evidence="ECO:0000259|PROSITE:PS51480"
FT ACT_SITE 218
FT /note="Tele-hemiaminal-histidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR612734-1"
FT BINDING 58..61
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR612734-2"
FT BINDING 109
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR612734-2"
FT BINDING 114
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR612734-2"
SQ SEQUENCE 575 AA; 60670 MW; 1C1B783032037B74 CRC64;
MTSTFKMINS PTTVVDEMLR GLVHSSPDLC LVSEYRVVLH RDFNDIKQRQ VTLLSGGGSG
HEPAHAGYIG HGMLTGVICG DVFASPSTSQ VLTAIRLAAG TQGCLIIVKN YTGDRLNFGL
AIETAKAEGI KVDMVVIGDD LAIPNAKAGR RGLAGTVFVH KVAGAMAAQG FPLDKIAEQV
QHLVIGTMGV AWKSCTLPGQ TSSRHIQPHE MELGLGIHGE PGAKTIGQLP SQATVAELMT
TIQNGIQVAR KDRVVVMVNN LGSMTSMELQ LIVNDVRQSC AKHDVVVERV AVGSFMTALD
MAGFSLTLWK LSPQHSTQQL EWLDASVTAP AWPVRLGRFV DNNVVNFAAV IPPSIQSTST
LTAAGEQLKR AIIAATQSII DAEGDLTEWD TKVGDGDCGH TLATGAKAIQ SALSDFPLNV
PSMTLADIAR AVGSAIGGTS GVLYTIFFTA AGAMMQTFDS KNDVVEVPLQ AWVESFAAGA
GAIVKYGGAT EGSRTMLDSM LPAIRAARRT DIPRADWIEA VKNAALEGAN STKRIAAHEA
CGRTSYVAED HVKDVPDPGA MAVAIWIQAI AQASL
//
