ID A0A024UK97_9STRA Unreviewed; 4406 AA.
AC A0A024UK97;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=UBA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=H310_02575 {ECO:0000313|EMBL:ETW06282.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW06282.1};
RN [1] {ECO:0000313|EMBL:ETW06282.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETW06282.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI913955; ETW06282.1; -; Genomic_DNA.
DR RefSeq; XP_008864357.1; XM_008866135.1.
DR EnsemblFungi; H310_02575-t26_2; H310_02575-t26_2-p1; H310_02575.
DR EnsemblProtists; ETW06282; ETW06282; H310_02575.
DR GeneID; 20079625; -.
DR VEuPathDB; FungiDB:H310_02575; -.
DR OrthoDB; 2916270at2759; -.
DR GO; GO:0008152; P:metabolic process; IEA:UniProt.
DR CDD; cd16449; RING-HC; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR15600; SACSIN; 1.
DR PANTHER; PTHR15600:SF42; SACSIN; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 578..617
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 4357..4393
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 4244..4267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 4313..4340
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 4250..4264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4406 AA; 485921 MW; 1E134218BD1046FA CRC64;
MSAPEMTEAV SFGDDFGQKI DLTVRIREIL RNYPEGTSVL KEMVQNADDA GATEISFCLD
KRTHASDNLA YTKLAVFQGP SLLVHNNAEF TDVDFESIQR IGDSLKKDSS KGWKTGRFGI
GFNSVYHLTD FPTFVSGRRI VMFDPQATHL PNVNPSNPGK LIDFLARQDL LAQFPNQFAP
FKGFGCNLAA HFHGTMFRLP LRTANEARRS KLSASIRTCE DIQHLLDEFF VESTMVLLFL
RHLAKISIYE WTDGQDAPSM RYTTAAAAVV ESLACRSQIV ARPPFSQAGT SWDVHLKVTT
RDIAHNMDHH ASWLVCNQLG GGTCSMIANH PDNASLRLIP YGGVAARLDA AVPGRAFCFL
PLPVETGLPV HINGYFELSS NRRDIWTGDG LSGDGLLRAQ WNDALLKDVI APCYARAIAT
IRHESPYLFP SHVPAIAWQK ALVLSMLRLI QTQPCLFARA TNSFVSPAEA KVLPVDMPHR
NTVEAVLQHD SVPLLSLDLS LQRLLLDTRT IPAPFAPQDA RSWYKAHRTS HGSDPVAMRH
LTEFCFDDIN STNSQEIVGV DLVPLLDGSV GTFQDGAGVD ADALAQLSAM GFDKTSCVAA
LTTTHDASEA LNWLLSHDAT ASSSTAAAMT TYYVCGDPLE LELLQASCSN VLVNTAVLSK
RMVALVTSVR HLNVERVTID SFRYLVGRHV FPSEWKHQQR VAKWSQDPPL SFAWFQSFWS
YVGPSPAKFE LFQDEWPVLP TKSAALCALH RQSTVVSGEL LPDAVVAILD TIGVDMLAPR
LFQNTPHHTI WNFIQQPTPH GVLATLSRAM CQALSMDDKA TMRDFLLSDH CHDMDNDAVQ
HLKSLPIFPG VDGAISITPS TYVAPQVDVE LLAQDDPHCM MPNVLSSAAT RVLNVHVLDK
MTFYWTKLFP AMPAMAIDRQ HAAIECVLRD VSLFLQRPLG PFQDLAIFPT MAAGPLKRIT
ELYDPEIDMF VGMIHPSCFP VAPSPDALAA MRLLGLQQML TRPSICQLIV ALASAELPDV
HRAKEFVTYI DTHADTLLHP TENVAKPSKK LPFFLKPKKI HTTATHLADE MKEIIALRDS
LTSHAWLPVL TTGTDAAQPM RTPVVTLALP RDVRLTDDMW LCSASCYILD GTITSDALRE
LFGWKRALPP AVLVRQLCAM HQMPSRSPAY STATCRIYEA CGRHPTDMVR PLLADAAWIW
IEDTFYTSSQ VAVECYIHAS PYLAAVPRAL DRFASFFKSM GVRQTFQAHD YVSVLQAMYD
AKLSGNNVAL RQDELALAVQ LIQALSDMPR PSTGRPVYMP SANATLQEAT TLAFNDAPWV
DPPPPHLVFV HSQISNVVAA SLGCISFRSC LVLATSEHLQ GVESFGQSEP LTRRLASILE
QYPEGTSILN ELVQNADDAQ ATQFSICYSR KTFKSSSLLS APLGLWQGAA LYCYNDAVFR
DSDFANLARI GQGSKLGNLS TTGRFGLGFN SVYHLTDVPS LVSGESLVMF DPHATNVPNA
TATHPGIKIR LTNSSLVGHF PDQFAPYALF GCDVASHRFD GTLFRFPLRN ADTGARSDIK
KGVYTDAQML EFLDLFKQSL TSTLLFLRHV SRISVYILDE GDDAPTLLYE GSVHERPPHP
LNQFPTKAAF YAHLAKQTAV AVQTNRIHVT TSHNSDDMYW ITHAVGCGLA QEMALANQAL
KLIPYAAVAA RVGDPLDGRA FSFLPLPVKV GLPVHINGYF ELSSNRRDIW HGDDMTGEGK
QRSEWNTRLL VDVVVPAYAA MLQTAQLDLP NNDVLALFPA AMPPCPWNLV VAALFRVIRD
IPLIRTEPTR DAVPLSNVVV SDSLSPRTTV LERLLRESNI PFAVLPPGLA CLVVDLKVVL
GSLTSSTFRH LLRTHRIRID ALPRPLVPDV VAICTEDGAL SELDGLPLLA MQNQTFRQLV
LKRAIAETVF CTTALENELL DGCGYADRRL NMDLCGHVLC AVPGLTDASN VKSYSLGEPS
LPLFPKTWHG QELVPWDPTS SHVSASWLRT FWTYVTAYVE TNGDGTVLHE WPCKPCMLPD
RTLVLVQLQV PTLVVDDSLV GNPFVRSFFT PLGQYILETP LLPHKECPPW LVNHSYCTFL
TSTSLIHLLA RHPHAIQTAS LHEREMLLAI VCQQLYNDYS DGQRTVIHTL ELFRVHGGND
RTFVSLESQL PLVLAPIDCN PALLGTSFLR PQGLTERQFC RDAGIPEWTQ DQVFLEHVLP
CLANYARPMQ LNILIDSLAS FTHASAAYQD ALKAVLVVPT QSSSSPLRRV SELHDPTKPD
LAGLLGPTSF PTQDLCTPTL LDVLRQLGLK QHLSVQAMAE SAAAIDDMSR RNRSEDAHAR
ACHLLAIVNE HLDSLYNPTT DAPHLTALAT LCWLPVAIER AHPLLPWRQT QYVASPDTTW
AQDMAWLGSS SKCILLGHVE SKTLASAFNW NVTSTVVVAQ LKALSEFSTC DTAEAQADMT
HHVRDLYVAL LTLPVDEWRP SLEEIAWLWT GFTFVKVSQV ATGCPPNLEP LLCPVPSASL
VPTDLLDAFA IKDAFDSSDY IHALQSLPQT RRLSDREMDV ALALLAWIHT TMDNTSIPSI
GTDVLLPDAD LRLVRAANLT ADDMAWNPAQ DIRCHRRLVH PNVPVELALR LGATSLHTSI
ASASSSSVKM GLPPVPVVLA NLNHPDAWNL QLFRAVTALA DKWHVSHVDF VLDQRHHPRE
KVCRPTFQSL QEESLLIHFH DHVMSADELY GDIHAIFTGL YVANCVQVLA GDAFYVVDPC
GIYVDVPGAI CYAVQSTEFQ RYSDQLVPFT CLPLAPSNPT SGFSGTVLRC PWRKLPCDSF
PACPVINTAA LVAQLDAAVK EAAAVSVLFT QYLSRVTLWT LGVGSEYARD CNVDIQLYDD
ASVLCARRKL VQDSEWKKPP VFQLSSFFRR SVKEELATVV ECTVRVETNN VPRVQRWLVS
SNVAVGRTRE VAKSMHGITP HASVACLLHQ SDGGTHVVGQ MCTTVPSGTA TGLPVHINGG
FLLAGLDLPL QGFGASDNQY DTKAMWNRIL IEDAVSEAYV QLLLAIKQAA SPWLEAAKAV
YRAWPSIHDP NDHHHVVGPF TQHAVLSKLS TQPLFLCGDG TMRKLDDGYD PATLHIQVAS
YCHLHFAMFQ LPTHVYATVR EHGAAIPQMQ PRVLRDFLKR VHVSTIHCAL CMPLLEYCAS
DLTSTTYHEL AGLPLLPLAD GSVGLIPYGH HIFTDKFVVA TMDQQQLLPT LCARFLALHF
VHSMAAWLAD PKFVAAIGAQ HFSVQLLATS LDTQLPKTWK NQTSVRWDHR VVDDLWLVRF
WSQVSKADAS LFQAWPLLPV SGGRELMSCR YVDRVIWLWQ DVSLAVELRA LVRQGHDRVR
EDLTALERES RVLESLTRKQ LDVFLEDDAV VDSPTIVAEP DNAAPHTHRS SETCDAILPV
PENDPAHRSI VDILSKLHAP SMEVAYFHEN VTFPLPTAHV GILGCLAQWP ERLEWAGMSA
ESKAALVYFF ASRGSSYGGY NRAQIDQLRR LPMYKTLSGQ HVAITDDVVM LSSEISTFPP
YLPDHVQGSF LELDPATSSV VVPFYKELRV DALSEAQLFI QFVMPQFQTT QAPAQTHAML
DMIHRKWNVM QDKPELLAFL QRTPLFPCAT GGYVCAYNFF DPRLPLLKAM FIESSPEFFP
PPHYSSDSWL AILGAIGMPT TISPDILLRC ACHVSHFTTP LTRSTEELVI MLHQHLVTLS
FVETHAENAF VAKLKAIACV PATVYSPVDG THLTKLVRYD ECAVPDDQFV ACFAKPILHS
YAVPPRILWR RVGLVSPPVV ADVIQHVSAI ALHAPNLVET WSFSFAVTDM FLAIFSFLQT
HWSDVTPPFR AQLRDMPLVP IGARLVKANR LYIRLADNLA PFLFEVPRVF GGCDALFRDL
GTTPAPQADD YIALLHALHD ECPVLNLNEL DAVIKILGLI EAFPDDSTAT LPVPTTTNRL
ARLHECVFND APAMLADIDG SHLHVVHPRV GPAICHHLRV PNLTAAVVEV LAPSFVPDRV
HDTTELTARL RSPEFSAGLQ QIIQASDFPG PAAGALDLPL WPLFTVVGVR DIPTRYVVAS
TGQDVTSSDS RPSKLFFVDA DRHLMYVRTE PPAVSLVHAV ALGVQHALHG LLKDSLPVVA
LLQTAGGDPT NMLRSLGLRT APDADATRGQ VGCRLVPFDK DRLELKPMRT FTEGEVVAVE
ANQAYVYAVV CGEKAVEVSG IQQVLVRTSS STTRWMRSTH VYSFKSERRP RGTAPSSATT
PRATRASVAP GAVAAIPPSP DAPPLPPAIL DHHVIDAVNG LLARLNLRLS APYESLVADV
MQLQQRVAAA EQSNAAMADR LNDALQVNND LVDSFVCSIC LEHHVDRVLV PCGHIFCHHC
THRIAPRKCP VCRHVFTLAS AFHKPT
//
