ID   A0A024UKF1_9STRA        Unreviewed;      1103 AA.
AC   A0A024UKF1;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=VASt domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=H310_02853 {ECO:0000313|EMBL:ETW06670.1};
OS   Aphanomyces invadans.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Aphanomyces.
OX   NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW06670.1};
RN   [1] {ECO:0000313|EMBL:ETW06670.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NJM9701 {ECO:0000313|EMBL:ETW06670.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR   EMBL; KI913955; ETW06670.1; -; Genomic_DNA.
DR   RefSeq; XP_008864745.1; XM_008866523.1.
DR   AlphaFoldDB; A0A024UKF1; -.
DR   STRING; 157072.A0A024UKF1; -.
DR   EnsemblFungi; H310_02853-t26_1; H310_02853-t26_1-p1; H310_02853.
DR   EnsemblProtists; ETW06670; ETW06670; H310_02853.
DR   GeneID; 20079903; -.
DR   VEuPathDB; FungiDB:H310_02853; -.
DR   eggNOG; KOG1032; Eukaryota.
DR   OrthoDB; 54126at2759; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR031160; F_BAR.
DR   InterPro; IPR001060; FCH_dom.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR031968; VASt.
DR   PANTHER; PTHR47666; PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR47666:SF1; TBC1 DOMAIN FAMILY MEMBER 9B ISOFORM X1; 1.
DR   Pfam; PF00611; FCH; 1.
DR   Pfam; PF02893; GRAM; 1.
DR   Pfam; PF16016; VASt; 1.
DR   SMART; SM00055; FCH; 1.
DR   SMART; SM00568; GRAM; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 2.
DR   PROSITE; PS51741; F_BAR; 1.
DR   PROSITE; PS51778; VAST; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1051..1071
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          16..295
FT                   /note="F-BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51741"
FT   DOMAIN          837..1014
FT                   /note="VASt"
FT                   /evidence="ECO:0000259|PROSITE:PS51778"
FT   REGION          789..816
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1016..1036
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1103 AA;  123763 MW;  4C05AD15E4E8E3CD CRC64;
     METTQTSTTQ ATGSAVETSC PPLSYQFHLF GAFNAVCSKG KNGIQTCQAI SSYLQERAAH
     EQVYSKQLAK IQQSVKTEDW AKHVANTWNT FHHTIAAISL EYAEFSNMHT SSIVSGMKAC
     TSQQESQIQR LITEGTKLRT QYIECMNKLT KAKERYERKC AEAIETIQTI RRPPVPDAAE
     KVDIFSKVWD NTTKGLGLGS MERQKQKITA CLDEVLSSED AYIRAVDTVN TQYDTYERQV
     HDNLMAFEVT EEQRLEYIKD LLVRSEKSRG AMMSRVEGLI TGMREALKSI DILDDIDDGF
     TTLLGLKTEG REEPELQFDI NPASITTLVT KMQTMSDQGV IFTHTMLNTL VECISAEETL
     VGALERIHAA SLPSSQLSEP ALFSSATPVV VAEGTTLARG WEAVLTHLQR VAHLHREFGS
     LLAEPVSLSL DTMKTEYIET KLRMEEQLQV VMASVSNEMA IHAKLEQKFE AKTKELAATK
     ASLAYSAQEK DAMLQRFMES PMDRERKLVL KAELLHEEVN NLKSQLEVNS AALSAKLLQR
     RQDICQIVSL CMKNEKYRLD VKKSSLRSLV KAHEHLVHGL LNASSKVRCD VDKINPGSDI
     KEFIQHAQVP WQAHDRLVPA LHGNIMLANE LKAHEKTPPK LARALSSLSI RTLDDVKDGA
     LNDKKPTADD APKDELFGHS DLQKNFNLPL SEQVVTSFTC ALYLNNFPHH GRLYLSQSFL
     CFSGWRDSYV VVPIMEVTHV EKKNTAIVVP NALELSTTKQ GKFFFASFLF REECIQSITQ
     LQQIKKQTQE ILSPGQPQSA PDTTKSTPTT ATDTTSALTN ATTTLDLADE QHILSNDYDA
     VLDVTLPFDL DVAFSRFWHP ADFLTSLLDS CGETNVDVGT WEIVETIYTA FQRQETFQGV
     RSVAYTHNKK YMVGPSSIPT MQIQRFKYDK TKCFVVSVTS TVSDAPYHDY FRAESRWLFT
     PSGPSECRLQ CGVRLNWVKS TWLKKQIESA TAAESKETMQ HWTVKATEAS KTPRVLAHTA
     DQSAAPPSPN LPEAPKTTAT IQSFRPNPRH FFTEVFVVVG IAIALHFVYS LHCMSSTLRN
     IVRVQFEQQQ LIEQILLKLS TSP
//