ID A0A024WG30_PLAFA Unreviewed; 1268 AA.
AC A0A024WG30;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Structural maintenance of chromosomes protein 5 {ECO:0000256|ARBA:ARBA00018687};
GN ORFNames=PFMALIP_06084 {ECO:0000313|EMBL:ETW45863.1};
OS Plasmodium falciparum MaliPS096_E11.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1036727 {ECO:0000313|EMBL:ETW45863.1, ECO:0000313|Proteomes:UP000030699};
RN [1] {ECO:0000313|EMBL:ETW45863.1, ECO:0000313|Proteomes:UP000030699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MaliPS096_E11 {ECO:0000313|EMBL:ETW45863.1,
RC ECO:0000313|Proteomes:UP000030699};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum MaliPS096_E11.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW45863.1, ECO:0000313|Proteomes:UP000030699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MaliPS096_E11 {ECO:0000313|EMBL:ETW45863.1,
RC ECO:0000313|Proteomes:UP000030699};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum MaliPS096_E11.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC5 subfamily.
CC {ECO:0000256|ARBA:ARBA00010171}.
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DR EMBL; KI925927; ETW45863.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A024WG30; -.
DR EnsemblProtists; ETW45863; ETW45863; PFMALIP_06084.
DR Proteomes; UP000030699; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030915; C:Smc5-Smc6 complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR InterPro; IPR027131; SMC5.
DR PANTHER; PTHR45916; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR PANTHER; PTHR45916:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR Pfam; PF13476; AAA_23; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000030699}.
FT DOMAIN 94..296
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 257..337
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 373..435
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 812..853
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 948..1003
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1047..1077
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1268 AA; 152407 MW; 1AC35E95327A3E07 CRC64;
MRNLNKRKLT CVENQSCKKR SRCDVGDKND NDIILKSENK TRKNIKIKVD KESKEKKGKN
INDKEQDDVI FMNDVDGYNT EYFKNLKKGA IIEMTLYNWM VFSGPITLRA NKGINLIAAA
NASGKSSIAC ALVFGLGYNS NILSRNKELI NFIKKGEKKS FIEITLKCDE EKKYICIKRI
MNIINNKVES FWFVNNKKEN YEKIEKIQKE FNLNLDNLIT FMPQENVSKF SRLNPEELFE
CTLLAIDKKL LDDYNYLKKK IEEKKTGENK IKTYEHEIIE EEKIINDLEK KKSKYENLRM
LLSRMKLYRV KKSLLLIEHK KKQVINIKEH IESLIKEKDT HFNTLKYYLS ELEKCHKVIN
NLSIEYSSKK IIIKESLNKY MKLNLTLEDM EKQIIKEEKI MDDTVQNIYE NKECIKELEN
KKKKIKEEIY KLEEFFNEKK DERINKILTI EQNKMNENPS IISKKIKNIN NTLNDDNQYH
NIKEKELQND LKKISDENKK LLMKKYNLQS EYKSILDKLK KRKNYKNIQE EKFLNSIEFT
LRERILNYKK NIKNIVETYN LLNKEYIENL KKKYDQTKLH NINEFNDEIV DELSKQNIIY
GPLCKYIKCI KPQYDYILEY FLKKYFNSFL LIQKDNKELL EVLYKKYKLS IITTNDKYSD
MNKDSINGNN IINYNDRNNN NNNNNNNAIP GYPKFCQVTN EMKKRGVEYF LYELFDSPEV
VKNSLINIVP IHISFIVKGD TLKNKSTKEI NEFNKFMINE ISKQLNEEVR SLFYFCEDNI
HRYRISTYDK NIFIENFSHI EKKKCKILFY MNKDVKKDID NLMERKEICE KELEELQIQF
SEFEKMKKEK NDEYNKIILE RNEMNIKKKK CTLLKNELIK IDENLDKYMK GENIIEEKKN
MILKNINLIN KKKIDICDEY LYILKEHSKY DKELFYIYHK LNQWKKYLSI IKNENIENEE
KHENLKNTIE IEKNKLNSYI YDINELNGLL KIQKNELSQE EINTLDTIHF NLEQVENKLK
ECIIQEKIYN NLDSNNNKCE EKYNILLLSI ERHKENVQNK IKQIDNLKET ISENEKQIHF
ILPQWSNQIN EYIIFLNYNF EKFMNFINPE FYGKIDLIKK NDIYEKCELY IKVKFKKNAP
FLLLSISHQS GGERSLTTML YILSIQKLTK NGFYVLDELN QGLDHINEQK IFQLLSCLSN
PIMYKQYFLH NYNYKYIHID YCSIPQYFIL TPQIIKNIVF KDITVHYLFN GFGVVDKQFD
NFYENYIS
//
