ID A0A024WIU7_PLAFA Unreviewed; 1898 AA.
AC A0A024WIU7;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Gamma-tubulin complex component {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFMALIP_05263 {ECO:0000313|EMBL:ETW46625.1};
OS Plasmodium falciparum MaliPS096_E11.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1036727 {ECO:0000313|EMBL:ETW46625.1, ECO:0000313|Proteomes:UP000030699};
RN [1] {ECO:0000313|EMBL:ETW46625.1, ECO:0000313|Proteomes:UP000030699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MaliPS096_E11 {ECO:0000313|EMBL:ETW46625.1,
RC ECO:0000313|Proteomes:UP000030699};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum MaliPS096_E11.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW46625.1, ECO:0000313|Proteomes:UP000030699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MaliPS096_E11 {ECO:0000313|EMBL:ETW46625.1,
RC ECO:0000313|Proteomes:UP000030699};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum MaliPS096_E11.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TUBGCP family.
CC {ECO:0000256|ARBA:ARBA00010337}.
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DR EMBL; KI925624; ETW46625.1; -; Genomic_DNA.
DR EnsemblProtists; ETW46625; ETW46625; PFMALIP_05263.
DR Proteomes; UP000030699; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005815; C:microtubule organizing center; IEA:InterPro.
DR GO; GO:0000922; C:spindle pole; IEA:InterPro.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR Gene3D; 1.20.120.1900; Gamma-tubulin complex, C-terminal domain; 1.
DR InterPro; IPR007259; GCP.
DR InterPro; IPR040457; GCP_C.
DR InterPro; IPR042241; GCP_C_sf.
DR InterPro; IPR041470; GCP_N.
DR PANTHER; PTHR19302; GAMMA TUBULIN COMPLEX PROTEIN; 1.
DR PANTHER; PTHR19302:SF14; GAMMA-TUBULIN COMPLEX COMPONENT 3; 1.
DR Pfam; PF04130; GCP_C_terminal; 1.
DR Pfam; PF17681; GCP_N_terminal; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000030699}.
FT DOMAIN 192..445
FT /note="Gamma tubulin complex component protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17681"
FT DOMAIN 1192..1460
FT /note="Gamma tubulin complex component C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04130"
FT REGION 124..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1464..1491
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 130..150
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1898 AA; 223845 MW; 8E9B560B715730C8 CRC64;
MIHEVILSLI GQTGDIIVLV HKNKKTTING NINIDDYRFE VNNNIHIFLN SEIKIINEIV
ELGYYFYIIN IFFLLVKKNT VYKNITHIHK YNKLNQERKN NKNLKNCNIY DKVNNGYYSS
GNDSFSSISS SSDDEEESDD ESDSDNDNEE EKNESASGYM TRKEHNKKNS YDNNNKNKMD
TYFGVILKNV KSINNASPYG YYANGICNEI KKFIKKYLKK ISDVEEYINN NSNTPLTQIV
TMLEKKREEL LVIINIIKNF LNFQKREEEN VIEGECRNKT KEILDYLYEH SLNGNSRIKK
IYHKYLKNVG KIFLHQLFSW ILYGQLIDPY NEFFIQKRQF IYSDEKKIYL TPEELYENLT
LSNVQSLNFE WNYLFFQSLN NLPQCCIDKI AGRKILFIGK SIRILIRSNK WNTSDILKLF
PIIKILSKAF DESSKFSLIH SSYYYKDDPN FMSNDPSFVK DGNEDENSNY SNSSSDNSSS
YADLSDSSND NINLYCKEIF DITIEKIRSI IAYKLWKYIV KDINLIKIFD LFKDIYLLNN
GDFYDYFLEK SWSLMHIPPN MKNEILLKSM AWKNSSVLVE EYCKSKYENK KDKLIIDNYD
NSLFTHIYSN NHDSKEEQSN FFFHNNANSS YYTFDTDTSE NFISKYFYPR ISYKKFSYDT
FEGEKFDNLI LGGMCYIYDN KIVLNDFYKG IQTLFKKKYY DYDNIFSVCI NNYRQQILRG
FKHGFDFSVN FNNFFDNQLY DQDITRNNIN EQNFVKDNNI SNKNYDGKNN EDHFLVGSCF
ALVIHSVNNP LLYKTDILNS SQGYWGTLGD CLSVEIRVKF YEKKKTINHP NINNNIQNNI
SDVILGDVEI EVSLYIGGKG ISSFVHNSNS YSIDYNKECI LNNKLLEDSL NQERERTYQE
DDHENDLKNI KKKGRIYPMG ISQEISNTSE NMRYSNNYYK DDNNSSYNIN NSSNDREQYP
VLKIQSNKQT FYNINKNTIT KFRVRINCLK HTFSVYIQKL DEYNLNFNNT KNKIKPIIHI
RALDMTQAFS LDIGNAYIGL YTCPILFKHK LLKKKSKLNE WFKNFYNVNM SDDMSTIYEK
NKNINIHNEN ANGTIENEIR NRDNLALNRN YQDTTKNNNN NNNIKYNREI DSEDDIFPYK
KRNIKNSENR LLFSCYDCSV EIYKWFHQSY KSAIEIPEID IDNETLIFYD KQINKNIKIH
SGLNLWNNIE IHFKLTWPIA LIINTNTIYT YNSIFQFLFL LSRIHYNLKI LCYHNRNLYK
YLYYGKGSSL FSYLFSIRYK MQFFFSHVIR YLQEDIINYE YKLMSTQIHK SKDFEYTKSV
HDLYISQIAT KCFLRIQDLT YPLMELIDTS FKFCYFFQCL VENELFTDIL NNEISNDKDN
HEHMKNEKKK KKDHSNIDTF IIDEDDKNED LKQVIEKLLQ YNDIFNDKLI VVINEMIGIS
SNNNHAYIIH LLTILDFNSY ITKIKDSRKK YNDLNSNKNS KNDEIKNLNK NIIEDDNVMK
ETHIDKTSHL QRNKFNINNS NDEKMEYQDI ENIHIIDNYD VDKNHSYNPN ISNLENNSTN
ILSQINIING INELNEKNTP LKSRIVNNFN NLLYNNIDLT SNIKPNDLSP YNQHMIMPQT
NEGFLNGNIN IGSETMLNNN KYNNYNYSYN NIMNSQNNII NSHNNIMDSH NNIINNHSNI
MNSYNNTANN NYNSLIDKYS NILNSYMNNT SSIYNSPKNF INNSNINSYN SILNTSKLRN
INNISSVSNN ISNDYNTNNI NKSSHNILHY DDNDDNNNIS NDIGSIPKQI KLSNINKSIY
DPNVLNNNNT TTDNIATNNL NNLMDIKVKN QFNVQNIIDQ YNYNTLSKNN ISLNNTYNIN
KISTLSPLNK VENTLNYSNI PLHIYHSENN TPKKSDHP
//
