ID A0A045IXQ4_MYCTX Unreviewed; 797 AA.
AC A0A045IXQ4;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=ATPase P {ECO:0000313|EMBL:SGH88404.1};
DE EC=3.6.1.- {ECO:0000313|EMBL:SGH88404.1};
DE EC=3.6.3.- {ECO:0000313|EMBL:SGH88404.1};
DE SubName: Full=Calcium-transporting ATPase 1 {ECO:0000313|EMBL:OMH58802.1};
DE EC=3.6.3.8 {ECO:0000313|EMBL:OMH58802.1};
DE SubName: Full=HAD-IC family P-type ATPase {ECO:0000313|EMBL:QGK78188.1};
GN Name=ctpE {ECO:0000313|EMBL:SGH88404.1};
GN ORFNames=A4S10_00961 {ECO:0000313|EMBL:OMH58802.1}, ERS007720_00434
GN {ECO:0000313|EMBL:COV54071.1}, ERS027659_00218
GN {ECO:0000313|EMBL:CKQ83106.1}, ERS053720_01878
GN {ECO:0000313|EMBL:CFH80857.1}, GJE03_04810
GN {ECO:0000313|EMBL:QGK78188.1}, SAMEA2683035_02235
GN {ECO:0000313|EMBL:SGH88404.1};
OS Mycobacterium tuberculosis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=1773 {ECO:0000313|EMBL:SGH88404.1, ECO:0000313|Proteomes:UP000182946};
RN [1] {ECO:0000313|EMBL:CFH80857.1, ECO:0000313|Proteomes:UP000046674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0351H {ECO:0000313|EMBL:CFH80857.1,
RC ECO:0000313|Proteomes:UP000046674};
RG Pathogen Informatics;
RA Murphy D.;
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OMH58802.1, ECO:0000313|Proteomes:UP000189452}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6548 {ECO:0000313|EMBL:OMH58802.1,
RC ECO:0000313|Proteomes:UP000189452};
RA Bigi M., Bigi F., Soria M.A.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:SGH88404.1, ECO:0000313|Proteomes:UP000182946}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2926STDY5723788 {ECO:0000313|EMBL:SGH88404.1,
RC ECO:0000313|Proteomes:UP000182946}, Bir 185
RC {ECO:0000313|EMBL:CKQ83106.1, ECO:0000313|Proteomes:UP000050164}, and
RC M09401471 {ECO:0000313|EMBL:COV54071.1,
RC ECO:0000313|Proteomes:UP000044938};
RG Pathogen Informatics;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:OMH58802.1, ECO:0000313|Proteomes:UP000189452}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6548 {ECO:0000313|EMBL:OMH58802.1,
RC ECO:0000313|Proteomes:UP000189452};
RA Bigi M.M., Lopez B., Blanco F.C., Sasiain M.C., De La Barrera S.,
RA Ritacco V., Bigi F., Soria M.A.;
RT "Protein polymorphisms may explain contrasting epidemiological fitness of
RT two variants of a multidrug-resistant Mycobacterium tuberculosis strain.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:QGK78188.1, ECO:0000313|Proteomes:UP000388593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AUSMDU00018547 {ECO:0000313|EMBL:QGK78188.1,
RC ECO:0000313|Proteomes:UP000388593};
RA Baines S.L., Goncalves da Silva A., Carter G.P., Jennison A.V.,
RA Rathnayake I.U., Graham R.M.A., Sintchenko V., Wang Q., Rockett R.J.,
RA Timms V.J., Martinez E., Ballard S., Tomita T., Isles N., Horan K.A.,
RA Pitchers W., Stinear T.P., Williamson D.A., Howden B.P., Seemann T.;
RT "Complete microbial genomes for public health in Australia and Southwest
RT Pacific.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CFSW01000010; CFH80857.1; -; Genomic_DNA.
DR EMBL; CNFT01000026; CKQ83106.1; -; Genomic_DNA.
DR EMBL; CSAJ01000031; COV54071.1; -; Genomic_DNA.
DR EMBL; LWDQ01000001; OMH58802.1; -; Genomic_DNA.
DR EMBL; CP045962; QGK78188.1; -; Genomic_DNA.
DR EMBL; FPTZ01000014; SGH88404.1; -; Genomic_DNA.
DR RefSeq; WP_003898639.1; NZ_WUCS01000006.1.
DR GeneID; 45424871; -.
DR PATRIC; fig|1773.206.peg.3573; -.
DR OMA; RLGRKQC; -.
DR Proteomes; UP000044938; Unassembled WGS sequence.
DR Proteomes; UP000046674; Unassembled WGS sequence.
DR Proteomes; UP000050164; Unassembled WGS sequence.
DR Proteomes; UP000182946; Unassembled WGS sequence.
DR Proteomes; UP000189452; Chromosome.
DR Proteomes; UP000388593; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd02609; P-type_ATPase; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF31; PLASMA MEMBRANE ATPASE-RELATED; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:SGH88404.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 50..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 633..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 667..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 702..722
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 729..749
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 761..784
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 797 AA; 84973 MW; 4C5034FC6052FC7B CRC64;
MTRSASATAG LTDAEVAQRV AEGKSNDIPE RVTRTVGQIV RANVFTRINA ILGVLLLIVL
ATGSLINGMF GLLIIANSVI GMVQEIRAKQ TLDKLAIIGQ AKPLVRRQSG TRTRSTNEVV
LDDIIELGPG DQVVVDGEVV EEENLEIDES LLTGEADPIA KDAGDTVMSG SFVVSGAGAY
RATKVGSEAY AAKLAAEASK FTLVKSELRN GINRILQFIT YLLVPAGLLT IYTQLFTTHV
GWRESVLRMV GALVPMVPEG LVLMTSIAFA VGVVRLGQRQ CLVQELPAIE GLARVDVVCA
DKTGTLTESG MRVCEVEELD GAGRQESVAD VLAALAAADA RPNASMQAIA EAFHSPPGWV
VAANAPFKSA TKWSGVSFRD HGNWVIGAPD VLLDPASVAA RQAERIGAQG LRVLLLAAGS
VAVDHAQAPG QVTPVALVVL EQKVRPDARE TLDYFAVQNV SVKVISGDNA VSVGAVADRL
GLHGEAMDAR ALPTGREELA DTLDSYTSFG RVRPDQKRAI VHALQSHGHT VAMTGDGVND
VLALKDADIG VAMGSGSPAS RAVAQIVLLN NRFATLPHVV GEGRRVIGNI ERVANLFLTK
TVYSVLLALL VGIECLIAIP LRRDPLLFPF QPIHVTIAAW FTIGIPAFIL SLAPNNERAY
PGFVRRVMTS AVPFGLVIGV ATFVTYLAAY QGRYASWQEQ EQASTAALIT LLMTALWVLA
VIARPYQWWR LALVLASGLA YVVIFSLPLA REKFLLDASN LATTSIALAV GVVGAATIEA
MWWIRSRMLG VKPRVWR
//
