ID A0A058ZNZ3_9RHOB Unreviewed; 1102 AA.
AC A0A058ZNZ3;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE AltName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN ORFNames=ATO10_06401 {ECO:0000313|EMBL:KCV82551.1};
OS Actibacterium atlanticum.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Actibacterium.
OX NCBI_TaxID=1461693 {ECO:0000313|EMBL:KCV82551.1, ECO:0000313|Proteomes:UP000024836};
RN [1] {ECO:0000313|EMBL:KCV82551.1, ECO:0000313|Proteomes:UP000024836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=22II-S11-Z10 {ECO:0000313|Proteomes:UP000024836};
RA Lai Q., Li G., Shao Z.;
RT "Shimia sp. 22II-S11-Z10 Genome Sequencing.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KCV82551.1}.
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DR EMBL; AQQY01000003; KCV82551.1; -; Genomic_DNA.
DR RefSeq; WP_035249541.1; NZ_AQQY01000003.1.
DR AlphaFoldDB; A0A058ZNZ3; -.
DR STRING; 1461693.ATO10_06401; -.
DR PATRIC; fig|1461693.3.peg.1297; -.
DR eggNOG; COG1074; Bacteria.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000024836; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR014151; DNA_helicase_AddA.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; TIGR02784; addA_alphas; 1.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000024836}.
FT DOMAIN 3..470
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 487..768
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT REGION 909..942
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 24..31
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1102 AA; 121495 MW; 009E31E79F8D0452 CRC64;
MKRDAATQAQ VRAADPIAST WLSANAGSGK TRVLTDRVAR LLLSGVSPQH ILCLTYTKAA
ASEMQNRLFK RLGEWAMLDQ ASLRDALERL GLEQSLNDDV LRNARRLFAR AIETPGGLKI
QTIHSFCAAL LRRFPLEAGV SPQFVEMDDR AANRLREDVL EALSDGPDTS AMDALAHYFP
GDDLNGILQE IAKHRAAFGA SASDIWQTFG LSPDFDENQL SQQVFLGDEQ QMLSDLIAAM
RGGTKTDVSN AEKLSRLLPD LPLADLEKLF LFGKSAQSPF GAKIGKFPNK AVLETLSFRD
ALEDFMRRVE AARPKRLALA AARKTLALHQ FAAAFLPEYN RRKQLHGWLD FDDLILKARD
LLTNPSVAEW VLFRLDGGID HILVDEAQDT SPLQWEVVEL LSREFTAGEG AHADTPRTIF
VVGDKKQSIY SFQGADPDGF DRMRDTFAGR LQAAPVPLSV QQLEFSFRSA PAILNVVDTV
FGEGRRAGMG DSVLHRAFRH DLPGRVDLWP VVEKEEKPDD LPWYDPVNRI APSAAPVRLA
NQLAARIKAM IGAESLIKDG ARRDLEAGDV LILVRRRSTL FHEIIRACKA AGLPVAGADR
LKIGGELAVK DLTALLSFLA TPEDNLSLAA VLRSPLFGWD EARLYDLAAG RKKKYLWATL
RARADDFRAE HDMLQALRDE ADYLRPFELL ERILTRQDGR RKLIARLGEE AEDGIDALLA
QALSYERSEI PSLTGFIGWL QSDEVEIKRE LGSAGNRIRV MTVHGAKGLE APVVILPDTN
KHELRIRDEI LEGPDGRALW KTATDQSPAL VADALDQLRL KQEEERQRLL YVAMTRAEQW
LIVCAAGDLD KGNSWYEKVQ LGMQHAGAVT HDFASRQGLR LETGDWPGPV GSAQSEDTLQ
TDLPDWLWHK APRPEKPAPA LSPSNLGGAK ALPGDAGLPE DEAKSRGTAL HLLLEHLPNH
PKDLWGRIAE QLEASDMLEE AVFVLTNEKL ASVFAEPALA EVDLTASLPA LGNAPLAGTI
DRLLFRDDHI LAIDYKSNAT VPPLAKDVPE GLLRQMGAYA SALKQIYPDT HIETAILWTA
TATLMPLPNQ LIDNALARAT TS
//
