ID A0A059D1Q0_EUCGR Unreviewed; 327 AA.
AC A0A059D1Q0;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Flap endonuclease 1 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EUGRSUZ_B01336 {ECO:0000313|EMBL:KCW84502.1};
OS Eucalyptus grandis (Flooded gum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW84502.1};
RN [1] {ECO:0000313|EMBL:KCW84502.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW84502.1};
RA Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT "The genome of Eucalyptus grandis.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK198754; KCW84502.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A059D1Q0; -.
DR STRING; 71139.A0A059D1Q0; -.
DR EnsemblPlants; KCW84502; KCW84502; EUGRSUZ_B01336.
DR Gramene; KCW84502; KCW84502; EUGRSUZ_B01336.
DR eggNOG; KOG2519; Eukaryota.
DR InParanoid; A0A059D1Q0; -.
DR GO; GO:0008409; F:5'-3' exonuclease activity; IBA:GO_Central.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd09907; H3TH_FEN1-Euk; 1.
DR CDD; cd09867; PIN_FEN1; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR HAMAP; MF_00614; Fen; 1.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR023426; Flap_endonuc.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR InterPro; IPR019974; XPG_CS.
DR InterPro; IPR006085; XPG_DNA_repair_N.
DR PANTHER; PTHR11081:SF9; FLAP ENDONUCLEASE 1; 1.
DR PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR Pfam; PF00867; XPG_I; 1.
DR Pfam; PF00752; XPG_N; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00279; HhH2; 1.
DR SMART; SM00484; XPGI; 1.
DR SMART; SM00485; XPGN; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
DR PROSITE; PS00841; XPG_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722}.
FT DOMAIN 1..101
FT /note="XPG N-terminal"
FT /evidence="ECO:0000259|SMART:SM00485"
FT DOMAIN 140..210
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT NON_TER 327
FT /evidence="ECO:0000313|EMBL:KCW84502.1"
SQ SEQUENCE 327 AA; 36383 MW; 0CE1A17BA28C4B67 CRC64;
MGIKLLADNA PTAMKEQKLE SYFGRRIAVD ASMSIYQFLF KKGTQMLNNE AGEVTSHLQG
MLYRTIRLLE AGIEPVYVFD GPPPDLKKQE LVKRFLKRAA ASEELAVAIA SQNKEDREKF
SKRTVKVTQQ HNEDCERLLR LIGVPVVEAT SEAEAQCAAL CKAGKAIASE DMDSLTFGAP
IFLLHLMDPI SRKVPVMEFE ISKILEEMNL DMDQFIDLCI LSGCDYCESI QGIGGLTALK
LIRQHGSIEN ILGNLTNKGI RHQSKAQLLL EEPIGLISFL ANKNGFNIER VMRAIEKIKA
AKDESSQGRL ESLFKPAKSL CVPAKRK
//
