ID   A0A059D2N1_EUCGR        Unreviewed;       743 AA.
AC   A0A059D2N1;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN   ORFNames=EUGRSUZ_B01285 {ECO:0000313|EMBL:KCW84440.1};
OS   Eucalyptus grandis (Flooded gum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW84440.1};
RN   [1] {ECO:0000313|EMBL:KCW84440.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW84440.1};
RA   Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT   "The genome of Eucalyptus grandis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; KK198754; KCW84440.1; -; Genomic_DNA.
DR   RefSeq; XP_010037291.1; XM_010038989.2.
DR   RefSeq; XP_010037295.1; XM_010038993.2.
DR   RefSeq; XP_010037302.1; XM_010039000.2.
DR   AlphaFoldDB; A0A059D2N1; -.
DR   STRING; 71139.A0A059D2N1; -.
DR   EnsemblPlants; KCW84440; KCW84440; EUGRSUZ_B01285.
DR   GeneID; 104426051; -.
DR   Gramene; KCW84440; KCW84440; EUGRSUZ_B01285.
DR   KEGG; egr:104426051; -.
DR   eggNOG; KOG2166; Eukaryota.
DR   InParanoid; A0A059D2N1; -.
DR   OMA; IREWDRY; -.
DR   OrthoDB; 21270at2759; -.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR   GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          388..618
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   743 AA;  86371 MW;  1840952489F9F0C6 CRC64;
     MANERKTIDL EQGWEFMQKG IMKLKNILEG QPEPQFCSED HIMLYTTIYN MCTQKPPHDY
     SQQLYDKYRE SFEEYIVSTV LPSLREKHDE FMLKELVKRW GNHKVMVRWL SRFFYYLDRY
     FIARRSLPPL NEVGLTCFRE LVYQELKVKV RDAVISLIDQ EREGEQIDRA LLKNILDIFV
     EIGMGQMDYY ENDFEAALLK DSAAYYSRKA SSWILDDSCP DYMLKAEECL KREKDRVAHY
     LHSSSESKLL EKVQHELLSV YASQLLEKEH SGCHALLRDD KVGDLSRMFR LFSKIPKGLD
     PVANIFKQHV TAEGTALVKQ AEEAASSKKG DKKDVVGLQE QVFVRKVIEL HDKYVAYVND
     CFQNHTLFHK ALKEAFEVFC NKGVGGSSSA ELLATFCDNI LKKGGSEKLS DEAIEETLEK
     VVKLLAYISD KDLFAEFYRK KLARRLLFDK SANDDHERSI LTKLKQQCGG QFTSKMEGMV
     TDLTLAKENQ TSFEEYLSNN TNANPGIDLT VTVLTTGFWP SYKSFDLNLP AEMVKCVEVF
     REFYQTKTKH RKLTWIYSLG TCNIIGKFEP KTMELIVTTY QASALLLFNS SDRLSYSEIM
     TQLNLTDDDV VRLLHSLSCA KYKILNKEPN TKTIAPTDHF EFNSKFTDKM RRIKIPLPPV
     DEKKKVIEDV DKDRRYAIDA SIVRIMKSRK VLGHQQLVME CVEQLGRMFK PDFKAIKKRI
     EDLITRDYLE RDKDNPNLFR YLA
//