ID A0A059D4M9_EUCGR Unreviewed; 387 AA.
AC A0A059D4M9;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177};
DE EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};
GN ORFNames=EUGRSUZ_B02005 {ECO:0000313|EMBL:KCW85175.1};
OS Eucalyptus grandis (Flooded gum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW85175.1};
RN [1] {ECO:0000313|EMBL:KCW85175.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW85175.1};
RA Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT "The genome of Eucalyptus grandis.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+) + indole-3-pyruvate + NADPH + O2 = (indol-3-yl)acetate +
CC CO2 + H2O + NADP(+); Xref=Rhea:RHEA:34331, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:17640, ChEBI:CHEBI:30854, ChEBI:CHEBI:57783,
CC ChEBI:CHEBI:58349; EC=1.14.13.168;
CC Evidence={ECO:0000256|ARBA:ARBA00035920};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|RuleBase:RU361177};
CC -!- PATHWAY: Plant hormone metabolism; auxin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004814}.
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183,
CC ECO:0000256|RuleBase:RU361177}.
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DR EMBL; KK198754; KCW85175.1; -; Genomic_DNA.
DR RefSeq; XP_010046265.1; XM_010047963.1.
DR AlphaFoldDB; A0A059D4M9; -.
DR STRING; 71139.A0A059D4M9; -.
DR EnsemblPlants; KCW85175; KCW85175; EUGRSUZ_B02005.
DR Gramene; KCW85175; KCW85175; EUGRSUZ_B02005.
DR eggNOG; KOG1399; Eukaryota.
DR InParanoid; A0A059D4M9; -.
DR OMA; KFFPNHW; -.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IBA:GO_Central.
DR GO; GO:0103075; F:indole-3-pyruvate monooxygenase activity; IEA:RHEA.
DR GO; GO:0004497; F:monooxygenase activity; IBA:GO_Central.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0009851; P:auxin biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000960; Flavin_mOase.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR43539; FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220); 1.
DR PANTHER; PTHR43539:SF9; INDOLE-3-PYRUVATE MONOOXYGENASE YUCCA11-RELATED; 1.
DR Pfam; PF00743; FMO-like; 1.
DR PIRSF; PIRSF000332; FMO; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Auxin biosynthesis {ECO:0000256|ARBA:ARBA00023070};
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU361177};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU361177};
KW Monooxygenase {ECO:0000256|RuleBase:RU361177};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU361177}.
SQ SEQUENCE 387 AA; 43358 MW; 52B243C4A3B3CCA3 CRC64;
MEKGNEKEVV VAIVGAGPAG LAAAACLNRQ GVANVVLERE DCSASLWRNR AYDRLKLHLG
KQFCELPHMS FPSNSSTFVP RAQFIEYLDN YKSQFEVKLY CQRSVERASY DDQTGKWRIV
ARNTGSGEHE VYVAEFLVVA TGENSEGMIP EVDGLESFGR EVMHSSKYRN GRGFRGKNVL
VVGCGNSGME IAYDLWNHGA NTSIVARSTV DVFTKEMVFI GMVLIKFLPR RIVDILMRLL
SKLKYGDFTK YGLRRPKNGA FHLKATTGRS PTIDVGAMER IKDGEIKVFP SIKRIHGKLV
TFVNDTTSQF EAIIFATGYK SNVRKWLQGG DDLFNVQGMT KVRDQWKGEN GLYSVGFSQR
GLLGIASDAQ NVANDINFEL RHRRKSK
//
