GenomeNet

Database: UniProt
Entry: A0A059KKZ1_9BURK
LinkDB: A0A059KKZ1_9BURK
Original site: A0A059KKZ1_9BURK 
ID   A0A059KKZ1_9BURK        Unreviewed;       688 AA.
AC   A0A059KKZ1;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   05-JUL-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=X805_25260 {ECO:0000313|EMBL:KDB51884.1};
OS   Sphaerotilus natans subsp. natans DSM 6575.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Sphaerotilus.
OX   NCBI_TaxID=1286631 {ECO:0000313|EMBL:KDB51884.1, ECO:0000313|Proteomes:UP000026714};
RN   [1] {ECO:0000313|EMBL:KDB51884.1, ECO:0000313|Proteomes:UP000026714}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6575 {ECO:0000313|EMBL:KDB51884.1,
RC   ECO:0000313|Proteomes:UP000026714};
RX   PubMed=24965827; DOI=10.1111/1574-6941.12372;
RA   Park S., Kim D.H., Lee J.H., Hur H.G.;
RT   "Sphaerotilus natans encrusted with nanoball-shaped Fe(III) oxide
RT   minerals formed by nitrate-reducing mixotrophic Fe(II) oxidation.";
RL   FEMS Microbiol. Ecol. 90:68-77(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KDB51884.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AZRA01000064; KDB51884.1; -; Genomic_DNA.
DR   RefSeq; WP_076458521.1; NZ_AZRA01000064.1.
DR   EnsemblBacteria; KDB51884; KDB51884; X805_25260.
DR   PATRIC; fig|1286631.3.peg.2473; -.
DR   Proteomes; UP000026714; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000026714};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000026714}.
FT   DOMAIN      385    519       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      596    665       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     393    400       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   688 AA;  73090 MW;  8E37BEE9BFE5E5B7 CRC64;
     MQTDLWDRGL ERLAAELPQQ QFNTWIRPLP PADVTVDGAA VRVDLCAPNR FKRDWLRSQF
     GERIERTLSE IAGMPVRLEL HIAGAREAAP ASATVPAPAS PPLPAGPPER ADPAPAETPG
     HDPVQMSMLD LPPAGGARGA ATPAASGARA RTRAGARKVA EPATPLVLAA DLSPLAESPA
     LARLAADAAA AASFISGRLD ATPPAPRPDR ASEPAVEPTR PIEVTAKPVA APAVVASPAA
     GAATASAAPV NASARPTDVL GAISASAALA KASAAVASRR RRAGAEDSPS PAPVPAPTGS
     SSASPARAAA PAPIVARQVP PAPAPGASGL AAPALVIPTV PPPSAPTSTR GRINPLLTFD
     TLVPGRANQM ARTAALHVVG SPGGMYNPLF LYGGVGLGKT HLIHAVGNAM LKEKQDARVL
     YLHAEQFISD VVRNYQRKTF DELKAKYHSL DLLLIDDVQF FAGKDRTQEE FFNAFEALVS
     KRAHIVMTSD TYPKGLVDID ERLTSRFDSG LTVAIEPPEL EMRVAILMKK AEAEGCAMPE
     EVAFFIAKNV RANVRELEGA LRKVVAYSRF SHKVINIALT REALKDLLSI QNRQISVENI
     QKTVGDFYKV KIADMYSKKR PASIARPRQI AMYLAKEMTQ KSLPEIGELF GGRDHTTVLY
     AVRKIAEERH KNTELNQQLH VLEQTLKG
//
DBGET integrated database retrieval system