ID A0A060NK14_9BURK Unreviewed; 543 AA.
AC A0A060NK14;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Choline dehydrogenase and related flavoprotein {ECO:0000313|EMBL:BAO81987.1};
GN ORFNames=SRAA_2133 {ECO:0000313|EMBL:BAO81987.1};
OS Serpentinimonas raichei.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Serpentinimonas.
OX NCBI_TaxID=1458425 {ECO:0000313|EMBL:BAO81987.1, ECO:0000313|Proteomes:UP000067461};
RN [1] {ECO:0000313|EMBL:BAO81987.1, ECO:0000313|Proteomes:UP000067461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A1 {ECO:0000313|EMBL:BAO81987.1,
RC ECO:0000313|Proteomes:UP000067461};
RX PubMed=24845058; DOI=10.1038/ncomms4900;
RA Suzuki S., Kuenen J.G., Schipper K., van der Velde S., Ishii S., Wu A.,
RA Sorokin D.Y., Tenney A., Meng X.Y., Morrill P.L., Kamagata Y., Muyzer G.,
RA Nealson K.H.;
RT "Physiological and genomic features of highly alkaliphilic hydrogen-
RT utilizing Betaproteobacteria from a continental serpentinizing site.";
RL Nat. Commun. 5:3900-3900(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
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DR EMBL; AP014568; BAO81987.1; -; Genomic_DNA.
DR RefSeq; WP_045532649.1; NZ_AP014568.1.
DR AlphaFoldDB; A0A060NK14; -.
DR STRING; 1458425.SRAA_2133; -.
DR KEGG; cbaa:SRAA_2133; -.
DR HOGENOM; CLU_002865_7_1_4; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000067461; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU003968};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968};
KW Reference proteome {ECO:0000313|Proteomes:UP000067461}.
FT DOMAIN 90..113
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 267..281
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
SQ SEQUENCE 543 AA; 58881 MW; 2D52C32C6D4DA0E2 CRC64;
MTPNPPTDAF DYLIVGGGSA GCVLAARLSA DPAVTVALLE AGGDGRDLAI RLPAGVVAML
PARPFKYNNW AFETVPQPGL LGRCGYQPRG KALGGSSAIN AMLYARGHRS DYDDWAAAGA
AGWSHAEVLP FFMRSEHNQR GPSAWRGVGG PLHVADQVSP RPIAQAFIEA CAQHGIAPNP
DYNGEEQEGA YLFQVTQFHD AARRGQRCSA AAAFLHPVLQ RPNLTVLTHT QATRVLFEGR
RAVGVQARQR GRHISLRARR EVVLCAGALQ SPQLLLLSGV GPPDELQRHG IPLVHRLPGV
GQNLQDHLDL TLSYRSTRTD LFGIGFGAAW QHWQAWRQWR RDGSGPLSSP SAEGGAFWRS
DAQQPRPDLQ LHFCVGIVDD HARKLHWGYG FSCHVCVLRP HARGRVGLRS ADPLAAPLID
PAFLSDARDL HLLSRGAQQM REILLRSPLQ PWRGTPLYDE QLHGDAAWEQ LIRSRADTIY
HPVGTCRMGV DEGAVVDAQL RVHGLQGLRV ADASIMPTLI GGNTNAPAIM IGERAAAWLL
AAG
//
