ID A0A060NRA4_9BURK Unreviewed; 4077 AA.
AC A0A060NRA4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=SRAA_2229 {ECO:0000313|EMBL:BAO82083.1};
OS Serpentinimonas raichei.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Serpentinimonas.
OX NCBI_TaxID=1458425 {ECO:0000313|EMBL:BAO82083.1, ECO:0000313|Proteomes:UP000067461};
RN [1] {ECO:0000313|EMBL:BAO82083.1, ECO:0000313|Proteomes:UP000067461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A1 {ECO:0000313|EMBL:BAO82083.1,
RC ECO:0000313|Proteomes:UP000067461};
RX PubMed=24845058; DOI=10.1038/ncomms4900;
RA Suzuki S., Kuenen J.G., Schipper K., van der Velde S., Ishii S., Wu A.,
RA Sorokin D.Y., Tenney A., Meng X.Y., Morrill P.L., Kamagata Y., Muyzer G.,
RA Nealson K.H.;
RT "Physiological and genomic features of highly alkaliphilic hydrogen-
RT utilizing Betaproteobacteria from a continental serpentinizing site.";
RL Nat. Commun. 5:3900-3900(2014).
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DR EMBL; AP014568; BAO82083.1; -; Genomic_DNA.
DR RefSeq; WP_045532781.1; NZ_AP014568.1.
DR STRING; 1458425.SRAA_2229; -.
DR KEGG; cbaa:SRAA_2229; -.
DR HOGENOM; CLU_223418_0_0_4; -.
DR OrthoDB; 4648428at2; -.
DR Proteomes; UP000067461; Chromosome.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 2.60.40.2030; -; 2.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR043824; DUF5801.
DR InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR InterPro; IPR001343; Hemolysn_Ca-bd.
DR InterPro; IPR047777; LapA-like_RM.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR InterPro; IPR019959; T1SS-143_rpt-cont_dom.
DR InterPro; IPR019960; T1SS_VCA0849.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR NCBIfam; NF033682; retention_LapA; 1.
DR NCBIfam; TIGR03660; T1SS_rpt_143; 2.
DR NCBIfam; TIGR03661; T1SS_VCA0849; 1.
DR Pfam; PF19116; DUF5801; 5.
DR Pfam; PF00353; HemolysinCabind; 1.
DR Pfam; PF13519; VWA_2; 1.
DR PRINTS; PR00313; CABNDNGRPT.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF51120; beta-Roll; 1.
DR SUPFAM; SSF141072; CalX-like; 2.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS00330; HEMOLYSIN_CALCIUM; 2.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000067461}.
FT DOMAIN 3301..3513
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 324..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1302..1333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2549..2574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2833..2861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3138..3159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2838..2861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4077 AA; 414227 MW; EBB889F7B8257450 CRC64;
MSQATVTSIT GNAVIVKADG TTRALQVGEV VQRGDVIRTQ AGARVELLLP DGQIMAMGPN
QALRVDETIA LTDATPQAAD AAVQPTTVAE IVQILEQGLD LLEQVDPAAA GAVAAGAGEG
SDFVRLLRVV EPVDPLAFQF SAAAADVDDV IEGAPAPVTV DLAFTLEEES VPLLEGNDEA
EDGLPFTLSG NFLTGIGGFL SSFSVPGLGF ITIADGGSTL AFDADGQVIP PGSTTAPAVL
LFVQPNGSYT LTVVGALNHP TPGTVEELLA LSPIALVGTA GSGGYLTINL QLNVQDDVPV
ALQDEGEGGL VPRADLIELD EDALEGGNTD NARPGETAGS GSASSSGTIV DNVNWGADGF
GRVTGVSWSG GSAAVQPNSS ATLFINADGT LGTADSAAIR LTLGADGAYQ FELLRAQTHG
AQGEDLQALL QGGFTISAVD GDGDPIVGGV RVNVDVLDDM PVIELVGPIP DDDNGYGDDF
PSNGDGPFPL PQLTVDETNF ALDDTSDPGT VHFSVRFGAD GPAVDGSKLY ALEAVADTDT
GLTDTATDQA VLIRLGTGAD AGKVFGVTET DGDTVFIMSV NATTGEITFD QQRAVVHGDA
TNPDDIVSIR EGVISLRLTA TDADGDTATA TVDVGSLVSI LDDGPSLKVG VTDAHTLDED
GLPGGNADAG RDGESTGSGS TSASGTIVDN VNWGADGFGR VTGVMVGGTA ATFNADAGTY
TISNDDYTLV VQENGDYTIT LNRAQAHGVQ GEDFKALLAS GFTVNAVDRD GDAVPDGVTV
NVGVLDDIPV IDVIDLSGSF TLTVTLKGSD AGYDNSFGYY IKDANGNPTT GVVIWDNVKD
FDVTQITLTG HTPVQVGFFI IPNGDRLNPN LGPNTAVTFQ QVNGNWQAVP VGGTAPLVGA
GASVLFDAVA LNPEGSAQVD DNADPGNLNW EDILGGGDGD FNDVNISYAW TSNLPVLTTQ
DADTIDTVTN STTTPVSDTA SASFASAFGR TYSYGADGAG TVESNYVLSI GSNGATGLTS
NGQPITLTME GGVVFGRTGS GSTAIDIFSI AVNPGTGQVT LTQFAELDHV GEDADSDAFN
NSAALLGLPA DVLFLTRTDT ITDRDGDVAR DSQTLDIGAA VRFEDDVPRL DANNGTDTVR
LDEDDLRAVR GTGESQGNDA APPEPLSASG SIVDNVNWGA DGFGRVTGVS WNGGTATVPT
GGSTTVFLGA NGQVQEGATG AAVSLLVNAN GSYTVTLLDN LLIGGAGENV VSLLQNGFTF
QAVDGDGDAV EGGVPVRIQI TDDVPVAVAG AAVSATVAEN DINTPLSSGT SPNDGNADGS
FTGDPGQSRG PAQVSGSLAT LVSFGADSAG ANGFGLATDF TALANQDLSS KGVDLSYAVS
GNTLTATAGI GQAARTVFTL ELQPNGNYTF RLFDQLDHAT GQGANSLALD LSSVIRATDA
DGDALTLSRG FTLNVTDDVP KLDGWKPAGG VVEEEALPRG NREWPNLGLV ESGSVSSQVE
AGADEGLRFT LNPLTGGLPT LTSGGVAVTY AVSGTTLTAS AGNTSVFTLV LQANGQYTFT
LRAPIDHASG NGENSRTLDL SSAIVATDFD GDALTLSNAL SITVIDDIPR DPDIEGPTWV
REDAASPITG TWSNAVGADQ AGSSIVVRVG SQDHALDSPI AVTVGNQNIG TLTVISGGTW
SFDPNPNLNN SSGVDFNFTI RVTDADGDTQ SDSHRITVKD GTDPRAGGSV TLALDEEALG
NANASGSNPT STLEQVQASV SFTAGSDDLL GFAFSNSLAQ LVRNTNAVTG DELVWTRSTD
GQTITATFVN TTQVALTLTL TAPTSIAHGQ TGNVTVTATL SDNLRHAIGN GEQVLNLGSI
QVVATDRDGD TAAATFNLSV KDDVPSITTS PTQALRESFE GFVTDEPNQG GWFVVGEGGR
TLTGNDGIVW TLNAAGIEIQ RGDVGGALPS DGNNKAELEA HNLAGGSPST LSVLSTRIDV
PGTTFGMSFD YQPRPADRAD SAMTVSLNGV QVTISADANG VVTVNAPSGV TVTQTPGSNG
WTGIALVFSG LTPGLQTLSF AGLSDNLDGD TLGAFLDNIR LSANNPLLVD ETLMGTDASG
GGAAQRFTVS FGADGAAASN GGKAYDLVAT NGAATGLTDT LSEERVVIRL GTGTNEVLGV
TEFGGRTVFV MSVNPTTGVV TFDQQRAVVH GNPNNPNDSV SLNPNVISLR LTATDGDGDT
ATATVDVGRL VSILDDGPSI DVALSTNGPA LPVLTTQDAQ TIDTVSGIVT TAVSDTASGN
FANRFTVTPT PSADGTSGAG THITTYALGV GQAVTGLTAG GLAITLYLGS NGKLLGSTAT
SAGGITPANT VFDISVTAAG QVTLTQHSEI DHAISGSLLG LNAGTVRLTA SASITDGDGD
TARDSETLDI SASFKFEDGT PPVVSISANP DTVNEDGTTN VTFTVSQDRP STTDTVVTIG
LTGTATEGTD YAVTGLTGTV TRTVTIPAGQ TSVTFSADPT PDILDEVNET VVATITAATG
ATVSTTASSA TATILDNDTA PTIEGASARV SEEGLPNGIP DTSGTPADST NSASASGTIA
LTGNGAAPLT VALALTGLPT SIGGTALTWS HGANPTVLIG SSGTTTPVPV IQITLNGGNT
AVAAGATSVG YAVTLLQPIQ HPSNSVEDVL PLSVGLSITD GVNTADAGLI HITIEDDMPV
ITSADNLTLA NQVTSQTGNI NGLLFGADGP ATAQALRLSG WPDLPGISET LSNDGKTLTA
TIDGSGSSPT VFYTLVLNDS GGYTFTLVTP QPTQTIAIGD QFGAGGRQET IAVTAGTNVV
TFDGLLFNNA AGVGAPQNHP EQGNNSDDLN PNDNGFGIQN GNLDHNEGFR ASMTSPADGL
SFTVEGFGGN VDQVTVEWRA YATDGTTVVD AGTLALSGLR TAGQLASIQS DAEFSRVDVR
FVMDSNESVR IQNFNVIDRI TPPDLALGFQ VTATDRDGDA VTANFTVNVN PSNVPTVQVG
APGTATGDIT VPEGDPAVFE VLVNHAAAGS TLVLTLADGT AVNPAISPAD YSRQVFEFSL
NGGTWTAYTV AIVLPAGSSS VLVRTNTVGD ALVEANETFT LGATLSSSST VVSDSATATI
LDNDTAPTIE GASARVSEEG LPNGIPDTSG TPADTTNSAS ASGTIALTGN GAAPLTVALT
LTGLPTLIGG TALTWSHGAN PTVLIGSSGT TPVIEITLNG GNTAVAAGAT SVGYAVTLLQ
PIQHPTNSVE DVLSLSVGLS ITDGVNTADA GLIHITIEDD MPAVPPAINV SINESGQSNH
NVMFILDLSG SMDDDALPAA GIQSRLSVAK DAMERLISTY DSMGEVKVRI VIFNDTASAV
GAEWMTATAA RTWINALAND AGNGFTNFDA ALNSAMTAFG SAGKIPAGVN VSYFLSDGEP
NRGSAPFIEN GPTAATADDS GIGTQEQAQW EAFLRTNDIK SFALGMGAGL VVNPGALDDE
LDPIAYDGVV EQNLNPIAVT DLSQLSQVLS GTVSSASTVS GNLLTDGNPD ARFGADGAGT
RPIHSVTFNT VEYTSASAPQ FNADTQTLTL QANGGTLSVN FATGAYSFTT SANPNDSTNA
FTYKIVDRDG DTAIGVLNIN VIDHNPVANH DSATAREGNW SLGTETNRTV KVLQPESWSA
STTTEVDGKW EIDPAHPGSV VTVQTPTFTF DANASNPATV RFDIDVDGYR SSDDVVRVEL
VNTAATGTPV QTRTFSGNAS DQTFSVTTGG TYFLRLVGDD NTSSGNLKAY LDDLQVTSRT
FTPARWVTQS VATPNMLWVA GLVAVGNVLA NDDVGIEGAV VSQVTVASTV ATVEATGNTL
IVGQFGTLSI NAQGAYTYTP NQRDNPNGAQ DVFSYTIRQP DGDTATANLT VNLTNFTYSA
AATDGAQLVG GGDGNDTLGG LGGNDVVYGG AGNDALDGGA GNDLLLGGIG NDTLTGGLGA
DVFAWRLGDQ GSTGTPARDV ITDFTPGQGD ALDLRDLLQG ESATNLGNYL RFDTEGTKLV
LLVDHDGGTG TFEATQHIVF DNFADRAALA QALGMSGTPN DADILTRLRE GGHLRTD
//
