ID A0A060SV48_PYCCI Unreviewed; 1349 AA.
AC A0A060SV48;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN ORFNames=BN946_scf184648.g3 {ECO:0000313|EMBL:CDO78031.1};
OS Pycnoporus cinnabarinus (Cinnabar-red polypore) (Trametes cinnabarina).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Trametes.
OX NCBI_TaxID=5643 {ECO:0000313|EMBL:CDO78031.1, ECO:0000313|Proteomes:UP000029665};
RN [1] {ECO:0000313|EMBL:CDO78031.1, ECO:0000313|Proteomes:UP000029665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRFM137 {ECO:0000313|EMBL:CDO78031.1,
RC ECO:0000313|Proteomes:UP000029665};
RA Levasseur A., Lomascolo A., Ruiz-Duenas F.J., Uzan E., Piumi F., Kues U.,
RA Ram A.F.J., Murat C., Haon M., Benoit I., Arfi Y., Chevret D., Drula E.,
RA Kwon M.J., Gouret P., Lesage-Meessen L., Lombard V., Mariette J.,
RA Noirot C., Park J., Patyshakuliyeva A., Wieneger R.A.B., Wosten H.A.B.,
RA Martin F., Coutinho P.M., de Vries R., Martinez A.T., Klopp C.,
RA Pontarotti P., Henrissat B., Record E.;
RT "The genome of the white-rot fungus Pycnoporus cinnabarinus: a
RT basidiomycete model with a versatile arsenal for lignocellulosic biomass
RT breakdown.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDO78031.1}.
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DR EMBL; CCBP010000604; CDO78031.1; -; Genomic_DNA.
DR STRING; 5643.A0A060SV48; -.
DR HOGENOM; CLU_000384_34_0_1; -.
DR OrthoDB; 1552858at2759; -.
DR Proteomes; UP000029665; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF13650; Asp_protease_2; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Aspartyl protease {ECO:0000256|ARBA:ARBA00022750};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Protease {ECO:0000256|ARBA:ARBA00022750};
KW Reference proteome {ECO:0000313|Proteomes:UP000029665};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 583..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 392..588
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 1302..1323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1349 AA; 151246 MW; BE660390D369A082 CRC64;
MARPPGCTFL GVQATTLEAR INSRDSEPIP VIVDSGSEIT LISQRTLAKL SEPPRIHQGQ
KVRLVQVTGN ATITGYVPLD LYFQTRAGTA RMTVEAYVVK GMTTPLILGN DFADQYSVSI
LRKEGETTVH LGDPSLEMIT CSSVSPTLRD DEGRAFQVHV KTRQERSTTT KKTRLRRIKQ
RHTRKAKDHS VRATEDVVVP PGTSRLVPIR AGFPEGVDSL YVERSLNVVR NIEDVYGAPD
TFINRFQPVM HVANLSDSPG HNGSDATQTF ATQAEAIGLP IDGSARTLEE DPLAEEPLEG
GPKTAEAPPE DVALSAFARE VDISDELDAS QRKQLLEVLI KNQKAFSLDG RLGTIKNSTC
SIPLRPGAKE VSLPPFPGSP AKREVMDAQM DKWIELGVIK PSVSPWGAPA FIVYRNGKPR
MVVDYRKLNE LTVPDEFPLP RQEDIMHALS GAQWLSTMDA LAGFTQTVID EQDHPKTAFR
THRGLHQFRR MPFGLRNGPS IFQRIMQGVL APYLWVFTLV YIDDIVVYSR TLEEHIRHLD
QVLEAVADAG QKVSRLGLST HQEKVKAITE LAPPRNVNDL HTFLGMMVYF SAYIPFYAWI
AAPLFDLLKK ERDWDWQDVH QEAFELCKQV LVQAPVRAHA IPGLPYRVYS DACDYGLAAI
LQQVQPIAIR DLKGTRVYDR LERAYKAGEP VPVLITQVAK GDPDVPSPGP WADNFDDTIV
HVERVIAYWS RILKAAERNY SPTEREALAL KEGLIKFQPY IKGEDVLAVT DHAALTWSRT
FQNVNRRLLT WGTVFSAYPK LRIVHRAGRV HSNVDPISRL RRRVPHQDGP TATDQPSLVL
GDQINDPLKN AFDELGPRFE ERLLKVAARY AHILTDPGRD DLSVSAVDMS DLVNVYDSDP
EERLAYVAAA SIALVIGIAP EELNEWKAAY LKDAHFRAVL ESFQRDDTEV LNQTLEIALR
AYISQARDDW SDHLDGLMLS YNCSPHTATN FSPAYLLRGY TPMTESTTMR PDEGIPRPFR
RQLAEGGERV ERVATDSSTH QVADEMAERF AADRHRAQQA LALGQAHQRK AYNKGRLRYE
FEEGDFVVLN PHSLQLLRQE TGRGRKLLMK YDGPFEIIQK LDLEEPRILQ FLKNVQNYNP
IRGRWPANVW YHAWQSLQIV GRETVEWVNE ARLRTRQSFG SSRWIFDEDD LNVRASWLGD
QPSSATDACA IHSLQTNTPL IPYDPTTPLF GSSESQPINP QSNSCRTVIP HPIYGTNADS
SLVAYERNKV PALLNELNNP CRALILHPVW STTAENGMVL HGGDRDTDSP SLPSAPPNSP
IISEASKSNF YSYEDIFGTG ADVEMDEDE
//
