ID A0A061AIW1_CAEEL Unreviewed; 451 AA.
AC A0A061AIW1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Choline/ethanolamine kinase {ECO:0000313|EMBL:CDR32638.1};
GN Name=cka-1 {ECO:0000313|EMBL:CDR32638.1,
GN ECO:0000313|WormBase:C28D4.2c};
GN ORFNames=C28D4.2 {ECO:0000313|WormBase:C28D4.2c}, CELE_C28D4.2
GN {ECO:0000313|EMBL:CDR32638.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CDR32638.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CDR32638.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CDR32638.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
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DR EMBL; BX284604; CDR32638.1; -; Genomic_DNA.
DR RefSeq; NP_001293883.1; NM_001306954.1.
DR AlphaFoldDB; A0A061AIW1; -.
DR SMR; A0A061AIW1; -.
DR EnsemblMetazoa; C28D4.2c.1; C28D4.2c.1; WBGene00000509.
DR GeneID; 177807; -.
DR AGR; WB:WBGene00000509; -.
DR WormBase; C28D4.2c; CE49764; WBGene00000509; cka-1.
DR OrthoDB; 144299at2759; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00000509; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR ExpressionAtlas; A0A061AIW1; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004103; F:choline kinase activity; IBA:GO_Central.
DR GO; GO:0004305; F:ethanolamine kinase activity; IBA:GO_Central.
DR GO; GO:0006657; P:CDP-choline pathway; IBA:GO_Central.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05156; ChoK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603:SF104; CHOLINE KINASE A; 1.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 1: Evidence at protein level;
KW Kinase {ECO:0000313|EMBL:CDR32638.1};
KW Proteomics identification {ECO:0007829|EPD:A0A061AIW1,
KW ECO:0007829|PeptideAtlas:A0A061AIW1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transferase {ECO:0000313|EMBL:CDR32638.1}.
SQ SEQUENCE 451 AA; 51795 MW; 6133D6A4A133A8D1 CRC64;
MVSLEVPTES PCISRRAPSE ECEIAFSHDD PTLMWKDRTT DCVDLKKVFS KFDSSAPISG
EILFRARFLC AKYLGGAWRK VKIEEFRIRA ITGGMSNLLF LVELPAHLTP IQMEPEKALL
RVHCQSDIDQ LLSESVVFTL LSERNLGPKM LGVFPGGRFE QFIPSRALQC LEISKPGLSK
LIAPIVARVH TLDAPIPKEP QTLQTARQWL ERFKKTPAGE RPIEMYLTQA KVPKSDIFQY
PSTITVAQLE RELNFVEFFL QHSHSPVVFS HNDLQEGNFL LIDGYKLADD GTVLTPDGKP
TNDDPLSLID FEYCSYNYRG FDLGNHFCEY GYDYNEAEAP YYKIHQHYFE VEKERKVFCE
AYLDEVYKMR ACGDNPHFPS DLVTGDREKD LNKIIEESIL FMPVSNIFWV CWSLINAEES
SIAFDYGAYG RDRLALYFHQ KKNLEKYLSN L
//
