ID A0A061DCP4_BABBI Unreviewed; 250 AA.
AC A0A061DCP4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=N-acetylglucosaminylphosphatidylinositol deacetylase {ECO:0000256|ARBA:ARBA00012176};
DE EC=3.5.1.89 {ECO:0000256|ARBA:ARBA00012176};
GN ORFNames=BBBOND_0307030 {ECO:0000313|EMBL:CDR96799.1};
OS Babesia bigemina.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=5866 {ECO:0000313|EMBL:CDR96799.1, ECO:0000313|Proteomes:UP000033188};
RN [1] {ECO:0000313|Proteomes:UP000033188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bond {ECO:0000313|Proteomes:UP000033188};
RX PubMed=24799432; DOI=10.1093/nar/gku322;
RA Jackson A.P., Otto T.D., Darby A., Ramaprasad A., Xia D., Echaide I.E.,
RA Farber M., Gahlot S., Gamble J., Gupta D., Gupta Y., Jackson L.,
RA Malandrin L., Malas T.B., Moussa E., Nair M., Reid AJ., Sanders M.,
RA Sharma J., Tracey A., Quail M.A., Weir W., Wastling J.M., Hall N.,
RA Willadsen P., Lingelbach K., Shiels B., Tait A., Berriman M., Allred D.R.,
RA Pain A.;
RT "The evolutionary dynamics of variant antigen genes in Babesia reveal a
RT history of genomic innovation underlying host-parasite interaction.";
RL Nucleic Acids Res. 42:7113-7131(2014).
CC -!- SIMILARITY: Belongs to the PIGL family.
CC {ECO:0000256|ARBA:ARBA00006066}.
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DR EMBL; LK391709; CDR96799.1; -; Genomic_DNA.
DR RefSeq; XP_012768985.1; XM_012913531.1.
DR AlphaFoldDB; A0A061DCP4; -.
DR STRING; 5866.A0A061DCP4; -.
DR EnsemblProtists; CDR96799; CDR96799; BBBOND_0307030.
DR GeneID; 24565340; -.
DR KEGG; bbig:BBBOND_0307030; -.
DR VEuPathDB; PiroplasmaDB:BBBOND_0307030; -.
DR OMA; HISTYET; -.
DR OrthoDB; 276931at2759; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000033188; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000225; F:N-acetylglucosaminylphosphatidylinositol deacetylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10320; LmbE-like; 1.
DR InterPro; IPR003737; GlcNAc_PI_deacetylase-related.
DR InterPro; IPR024078; LmbE-like_dom_sf.
DR PANTHER; PTHR12993:SF11; N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE; 1.
DR PANTHER; PTHR12993; N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED; 1.
DR Pfam; PF02585; PIG-L; 1.
DR SUPFAM; SSF102588; LmbE-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000033188};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 250 AA; 28598 MW; 2957023D70D842EA CRC64;
MQSEYWGPPL ICLFILVVYY GVRFYLNKKR LQLVPWMIYG LEGNGPHVVS FVLTHPNDEA
YYFSPTLEML GDFRQQYSSV DVHALVLSKG NYSGEGDSRV SEMQTICNKY KMQCTILDEP
DMQMDTPTWD KDRIAELVQK FLEKNSSKVV ITFDEHGVNS DSHRISAHDA VMAVKEKISD
LRVWMLASFG SASANFPLFA YLEAIFAKTI ACVHSFGPVY QNVKIHESES SSGFKLFFNS
YGYVNIFKRL
//
