ID   A0A061DN58_THECC        Unreviewed;       559 AA.
AC   A0A061DN58;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Glutamate receptor 2 plant, putative {ECO:0000313|EMBL:EOX91413.1};
GN   ORFNames=TCM_000618 {ECO:0000313|EMBL:EOX91413.1};
OS   Theobroma cacao (Cacao) (Cocoa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX   NCBI_TaxID=3641 {ECO:0000313|EMBL:EOX91413.1, ECO:0000313|Proteomes:UP000026915};
RN   [1] {ECO:0000313|EMBL:EOX91413.1, ECO:0000313|Proteomes:UP000026915}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX   PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA   Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA   Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA   Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA   Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA   Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA   Kuhn D.N.;
RT   "The genome sequence of the most widely cultivated cacao type and its use
RT   to identify candidate genes regulating pod color.";
RL   Genome Biol. 14:R53.1-R53.24(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CM001879; EOX91413.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A061DN58; -.
DR   STRING; 3641.A0A061DN58; -.
DR   EnsemblPlants; EOX91413; EOX91413; TCM_000618.
DR   Gramene; EOX91413; EOX91413; TCM_000618.
DR   eggNOG; KOG1052; Eukaryota.
DR   HOGENOM; CLU_487831_0_0_1; -.
DR   InParanoid; A0A061DN58; -.
DR   Proteomes; UP000026915; Chromosome 1.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR   GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR   Gene3D; 1.10.287.70; -; 1.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   PANTHER; PTHR18966:SF556; IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   4: Predicted;
KW   Ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023286};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:EOX91413.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..559
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001601058"
FT   TRANSMEM        496..519
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          277..504
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00060"
SQ   SEQUENCE   559 AA;  63092 MW;  D5EC5F6EDF3E5270 CRC64;
     MDSKMVFALL LVSLALLLLF PSINCSTGIG DTAGGGEFPD SFRAVSDCSF SSSVEFQQEQ
     HIAWEMSIRG FNGITGPKMA LTFQDLYGNS TPVVLSAFYG DKKGHMDDID IVTLVLTYCS
     NNKMRKLWAL IIMDDPISLS TTSSPLLGTI NNTFRGTYRS QDSSSGGAGN KMIDGALVIS
     NTTQFLSVNI NDKNYRTLTE LYNSFDELVE KVVVEVSHRY IKKWFHRAVG DIEITADHNQ
     PRVFYQRRSE SRFTMVVKAK PNELDRFWWF LSPFTLEMWL TLVALSVFTG FVTWIIEGQN
     EDGPNLVEAL LFFVHRDAPR NRLTNFVQVP WLFLVLVVTS TYTASFSSTV TSSETKPPCL
     DMENLKITNA IIGCDGDSII FRYLVETLGF KRKNIKNIAQ SSIDDYAEAL STGNIKAAFF
     STPHADVFLE KYRKGFSAWE PIRNLRDSTI VFPRVSPFVS EMSKFKQMKG YMLSFLDCSG
     STIDGTMKQG IGPGPFSGLF FLSGGASAIA MLITVIRLIE RRWENYIQRM LMGRELWVWL
     TTLFPRNQRR NELQIQVQG
//