ID A0A061EHD3_THECC Unreviewed; 764 AA.
AC A0A061EHD3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=TCM_011517 {ECO:0000313|EMBL:EOY01674.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY01674.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY01674.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; CM001880; EOY01674.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061EHD3; -.
DR STRING; 3641.A0A061EHD3; -.
DR EnsemblPlants; EOY01674; EOY01674; TCM_011517.
DR Gramene; EOY01674; EOY01674; TCM_011517.
DR eggNOG; KOG0922; Eukaryota.
DR InParanoid; A0A061EHD3; -.
DR OMA; NHKYIRN; -.
DR Proteomes; UP000026915; Chromosome 2.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003725; F:double-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0045943; P:positive regulation of transcription by RNA polymerase I; IBA:GO_Central.
DR GO; GO:0043484; P:regulation of RNA splicing; IEA:EnsemblPlants.
DR CDD; cd17978; DEXHc_DHX33; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF118; ATP-DEPENDENT RNA HELICASE DHX33; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EOY01674.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915}.
FT DOMAIN 98..303
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 321..500
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 764 AA; 85971 MW; 3B48BE5E464FABE0 CRC64;
MKIRGSAAEY LGNKNEQKQG FKLKYVFVWV KVKRLSLFFS CRAKMPSMAQ TPNPSANGNL
SFNHNNNNNN KPNFFARSRK ILEQRKSLPI ASVERRLIEE VRKHDILIIV GETGSGKTTQ
IPQFLFNAGF CRGGKTVGIT QPRRVAAVTV AKRVAEECGV ELGQKVGYSI RFEDVTSSST
SIKYMTDGLL LREALLDPYL SRYSVIVVDE AHERTVHTDV LLGLLKKVHN VRSKYIRDHT
SVGHKRTSDG AILEKENADP CISVLKQCEG RKLPPLKLII MSASLDARVF SEYFGGARAV
HIQGRQFPVD IFYTVNPQTD YLDSAIITIF QIHLEEAPGD ILVFLTGQEE IESVEKQIQD
NLRQLPEDSR KMSTAPIFSS LPSEQQMRVF APAPAGFRKV ILATNIAETS VTIPGVKYVI
DPGVVKARCY DPIKGMESLI VVPTSKAQAL QRSGRAGRDG RGKCFRLYPE SEFEKLEDST
KPEIKRCNLS NVILQLKALG VDDIFGFDFI EKPSRAAIKR SVEELILLGA LTDDCKLSDP
VGHQMARLPL DPIYSKALIL ASQFNCLEEM LIAVAMLSVE SIFYEPREKK NEARTAKNCF
ASPEGDHLTL INVYRASNDL LEKRKSEVGK DKHEKILRKW CKENFISSRS LRHARDIHSQ
IQQHVEQMGL CISSCGDDTL QFRRCLAAAF FLNAALKQPN KTYRALASGE VVHIHPTSVL
FHTKADCIIF NEFVKTSKEY IRNVTIIDGF WLTELAPHYY ARQE
//
