ID A0A061FZI1_THECC Unreviewed; 456 AA.
AC A0A061FZI1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=RING domain ligase2 isoform 1 {ECO:0000313|EMBL:EOY22287.1};
GN ORFNames=TCM_014506 {ECO:0000313|EMBL:EOY22287.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY22287.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY22287.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
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DR EMBL; CM001881; EOY22287.1; -; Genomic_DNA.
DR EMBL; CM001881; EOY22288.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061FZI1; -.
DR EnsemblPlants; EOY22287; EOY22287; TCM_014506.
DR EnsemblPlants; EOY22288; EOY22288; TCM_014506.
DR Gramene; EOY22287; EOY22287; TCM_014506.
DR Gramene; EOY22288; EOY22288; TCM_014506.
DR eggNOG; KOG1327; Eukaryota.
DR HOGENOM; CLU_035766_1_0_1; -.
DR InParanoid; A0A061FZI1; -.
DR OMA; HIGEEQN; -.
DR Proteomes; UP000026915; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR CDD; cd01459; vWA_copine_like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR010734; Copine_C.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45751; COPINE FAMILY PROTEIN 1; 1.
DR PANTHER; PTHR45751:SF38; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF07002; Copine; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:EOY22287.1};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 413..446
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..409
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 456 AA; 50829 MW; 6359C12360F4C745 CRC64;
MGGVTSKRSA TAQSSSVGSN SHSWDHQRYA QPSYAPSSRD YSWDHQRYAQ PSYAPSSRDY
VPQQHYAPPL QSYGGRAPES NRRLERKYSK IDDNYNSLEQ VTEALARAGL ESSNLIVGID
YTKSNEWTGA RSFHRRSLHH IGDEQNPYEQ AISIIGKTLS SFDEDNLIPC FGFGDASTHD
QEVFSFYPDE TFCNGFEEVL RRYRELVPNL RLAGPTSFAP IIEMAITIVE QSGGQYHVLL
IIADGQVTRS VDTERGQLSP QEMKTVEAIV RASDYPLSII LVGVGDGPWD MMREFDDNIP
ARAFDNFQFV NFTEIMSKNM DRSRKEAEFA LAALMEIPSQ YKATLELSIL GTSRGKDIDR
VPLPPPLYGA ASFSNSKPSR SSSFRPTPPS SGRYDAPVRT TPSASSASDN HVCPICLCNP
KDMAFGCGHQ TCCECGQDLQ LCPICRSTID TRIRLY
//
