ID A0A061GAV2_THECC Unreviewed; 877 AA.
AC A0A061GAV2;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Disease resistance protein RPS5, putative {ECO:0000313|EMBL:EOY26676.1};
GN ORFNames=TCM_028629 {ECO:0000313|EMBL:EOY26676.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY26676.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY26676.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM001884; EOY26676.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061GAV2; -.
DR EnsemblPlants; EOY26676; EOY26676; TCM_028629.
DR Gramene; EOY26676; EOY26676; TCM_028629.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_328014_0_0_1; -.
DR InParanoid; A0A061GAV2; -.
DR OMA; VRIRVEM; -.
DR Proteomes; UP000026915; Chromosome 6.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR CDD; cd06222; RNase_H_like; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR044730; RNase_H-like_dom_plant.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR33463:SF190; NB-ARC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR33463; NB-ARC DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF00931; NB-ARC; 2.
DR Pfam; PF13456; RVT_3; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915}.
FT DOMAIN 756..877
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT COILED 850..877
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 877 AA; 100357 MW; E5FCCA12E298DC1F CRC64;
MRRTEQVERW LTSVERFVNE INGVIEQGHQ QLQDTCLGSF CPKNLPSTYK IGKRIVNRLG
SARDLRHMSE SFFSISDFTI VERLPGLRLL MPELLVENTV GLDSAVERVW RCNKDENTQV
IRLCGIGGVG KSTLSKKLSN EFHIRNHDFD VVIWAEVSRQ EEGLYRETSR DDIREQFDLL
RLGIHLQMGN QNSSKVIYTT RSMELCNAVE ALETIEVKCL PPQQALKLFR MMVGENILNN
DPELSELAEI IALTCGGLPL AFLTVGRAMA SRRNPREWHL AVELIHSNPS EIDGFGDRVF
PLLKFSYDGL NNATAQKCFR YCYIFPKDYN VRIDELIGLW IGEGFFDGSN PRDQAEFIVG
TLKLAYLLES DEYKQFIGMH DVVHDMALWL VRDQGKRKKV LVTKGVTITY EEHKKWEEAN
WISLYGSRNQ GLVELPLDIG NVKTLQYLNL SLTSKVELPA SLTNLRSLRC LLLDYTTNLK
RVPKEALECL NRINKLGITI FAAPSVDNII KSYTLRSCIR KLTFMECNGL ISLRFTQELG
NLERLEIFRC CSLKEFKISE WCKLGNLRQD YIGVFPLLLN LDFLAYARNL VTLTILDCES
LESVTSEIIA FPGLKTISLT CLRNLESICP LPRCFPSLSE IEVSQCSLLR QLPFDLETAK
FLQKIRGKTM TLKEKERFFA VIWSLWLARN DIIFGGQTWD RAQTYELVKL RVATWAKAKW
PRDYNRTLDT FIEPRLGAVL ICVKKTRPKV EWTNPVDGSM KFNVDGAASG CPREAGIGGI
LRNSAGETKM MFSKSIGMGD SNLAEVLAIK QAFMMFFASN WNGSHSLVIE SDSSNAVSWI
QAPNQALWRM RKWILQIEML ERKVKRWEIK HVKREAN
//
