ID A0A061GH40_THECC Unreviewed; 523 AA.
AC A0A061GH40;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=tRNA(His) guanylyltransferase {ECO:0000256|ARBA:ARBA00012511};
DE EC=2.7.7.79 {ECO:0000256|ARBA:ARBA00012511};
GN ORFNames=TCM_030226 {ECO:0000313|EMBL:EOY28703.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY28703.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY28703.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the tRNA(His) guanylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010113}.
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DR EMBL; CM001884; EOY28703.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061GH40; -.
DR STRING; 3641.A0A061GH40; -.
DR EnsemblPlants; EOY28703; EOY28703; TCM_030226.
DR Gramene; EOY28703; EOY28703; TCM_030226.
DR eggNOG; KOG2721; Eukaryota.
DR HOGENOM; CLU_044271_4_0_1; -.
DR InParanoid; A0A061GH40; -.
DR OMA; ILVWINA; -.
DR Proteomes; UP000026915; Chromosome 6.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0008193; F:tRNA guanylyltransferase activity; IBA:GO_Central.
DR GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IBA:GO_Central.
DR Gene3D; 3.30.70.3000; -; 2.
DR InterPro; IPR025845; Thg1_C_dom.
DR InterPro; IPR024956; tRNAHis_GuaTrfase_cat.
DR InterPro; IPR007537; tRNAHis_GuaTrfase_Thg1.
DR InterPro; IPR038469; tRNAHis_GuaTrfase_Thg1_sf.
DR PANTHER; PTHR12729:SF6; TRNA(HIS) GUANYLYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR12729; UNCHARACTERIZED; 1.
DR Pfam; PF04446; Thg1; 2.
DR Pfam; PF14413; Thg1C; 2.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:EOY28703.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 6..134
FT /note="tRNAHis guanylyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF04446"
FT DOMAIN 139..224
FT /note="Thg1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14413"
FT DOMAIN 274..402
FT /note="tRNAHis guanylyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF04446"
FT DOMAIN 406..501
FT /note="Thg1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14413"
SQ SEQUENCE 523 AA; 61113 MW; 0B50611AB136B36D CRC64;
MANSKYEYVK SFEVEDEVMP PNLIVVRIDG RDFRRFSQVH EFEKPNDKKA LDLMNQCAMA
VIEEYPDVVF SYGYSDEYSF VLKKTSKFYQ RRSSKISSVM VSIFSSVYVT KWKEFFPCKE
LRYPPSFRSR IVCCASIEVL QAYLAWRQKD CHVQNQYNTC FWELVTKGGK TEMEAQEILK
DAKEQDRNEL LFQQFGINYN ECLALFRQGT CIFKMQVEDV VKYIKDGTPV KRLRRKASDF
RSENIAGRSF WNEHASLLKE LGGFSEDCVK INPDYIRSFL FESKLMPSTW IVIRIDGCHF
HRFSDVHEFN KPNDKQALDL MNLCAVAVLE EFQDIIFSYG VSDEYSFVLK KNSQLYQRRA
SEIVSAIVSF FSSMYVMKWK DVFPMKELKY PPSFDGRAVC YPSAEILRDY LAWRQVDCHI
NNQYNTCFWS LVKSGKCKSE AQSCLKGTQA REKNELLLKE FGIDYNTLPL MFRQGSSVFR
VKTEKTSILE NSTSVGKAQT KIVTEYCNII EQSFWEANPS ILD
//
