ID A0A061J9Q7_TRYRA Unreviewed; 1049 AA.
AC A0A061J9Q7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Calcium motive P-type ATPase {ECO:0000313|EMBL:ESL10017.1};
GN ORFNames=TRSC58_02255 {ECO:0000313|EMBL:ESL10017.1};
OS Trypanosoma rangeli SC58.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX NCBI_TaxID=429131 {ECO:0000313|EMBL:ESL10017.1, ECO:0000313|Proteomes:UP000031737};
RN [1] {ECO:0000313|EMBL:ESL10017.1, ECO:0000313|Proteomes:UP000031737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC58 {ECO:0000313|EMBL:ESL10017.1,
RC ECO:0000313|Proteomes:UP000031737};
RA Stoco P.H., Wagner G., Gerber A., Zaha A., Thompson C., Bartholomeu D.C.,
RA Luckemeyer D.D., Bahia D., Loreto E., Prestes E.B., Lima F.M.,
RA Rodrigues-Luiz G., Vallejo G.A., Filho J.F., Monteiro K.M., Tyler K.M.,
RA de Almeida L.G., Ortiz M.F., Siervo M.A., de Moraes M.H., Cunha O.L.,
RA Mendonca-Neto R., Silva R., Teixeira S.M., Murta S.M., Sincero T.C.,
RA Mendes T.A., Urmenyi T.P., Silva V.G., da Rocha W.D., Andersson B.,
RA Romanha A.J., Steindel M., de Vasconcelos A.T., Grisard E.C.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESL10017.1}.
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DR EMBL; AUPL01002255; ESL10017.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061J9Q7; -.
DR EnsemblProtists; ESL10017; ESL10017; TRSC58_02255.
DR VEuPathDB; TriTrypDB:TRSC58_02255; -.
DR OrthoDB; 203629at2759; -.
DR Proteomes; UP000031737; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF14; SODIUM TRANSPORT ATPASE 1-RELATED; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ion transport {ECO:0000256|ARBA:ARBA00023201};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000031737};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023201}.
FT TRANSMEM 100..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 843..865
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 885..906
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 918..941
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 956..978
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..120
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1049 AA; 115482 MW; 0543F04F86998FBB CRC64;
MRRTQGIRSN MPDSSELSPR EPINGNIPPT ERHEPVLDKY NPFYNWWTFD IQHTLELVQL
DDVANGVSDD DVFRRAAELG NNKISIAGAP NPIWIFCRQF MNSITLILTI VIVISAISAD
WPEFGVVLFI LIFNALLGFY HEYRAEKSLH SLKEMTAGSA KVLRDGSVEV IFIDEVVVGD
VIILEQGASV PADCRLVESS GLEVDEALLT GEALPVVKHI AAIPDPDGMC ALGDRKNMVY
RNTTVTQGHG KAVVVAAGVH TEIGKLAERL GEDSGTEKTE LMKTLDYMMY LLFGCCIVLV
VVVFAANKFK YHPSTLSYAT AVAIAILPES MVAVVTVSMT VSVKRMAKQK CIVRRLAVLE
VLGNVTDICS DKTGTLTENK MTVKNIIVGT NDEITVTGAP DERYGVFMHR EEDQVYMVGA
YATNKLLYEF MRCAALCGTT VLKVDAQDAD RLCGTGNPTE VAIQVMSWKA GLYRAQLESE
GWECIAEYPF DSKIKRMTTV WYNKITDSLY ICTKGAPERI LDLCSTIVSE SGRHVALAES
DRQTIDNNIG KLALGGLRTI CLSMRPCTLK QFAIPAEGAF MATHAREVIE QDLSFLGIVG
IYDPPRPESL PSVIACQHAG IVVRMLTGDH VTTAGCIAAA LNIIDKTDLD NSMKLLSGPE
FDRTEMEAIA EWGDLPLVVG RCSPESKVKM IECLHKRKRV VAMTGDGFND SPSIKIADVG
CAMGSGTDVT KGVADIIITD DNFSTIVKAV TEGRRISQNI RKFVVHLLSS NVAEVIALIC
GLPIRSEGVS LFVLSPIEIL WLNMFTSGPP AIGLSLDTAA ADVLLVPPNT AGLFTLELVS
DTVVYGFWLG LCSLCGFVFI VYGVHDGPSG TNCNSHKGVG CQEVWRARAT AFGILYFGLL
LHAYTVRHTR QSVFLMKWFD NVLIYVSISV AAGLFIVILY VDVVAHNVFV HDMLTWHWAV
IGVLLLFFMA VCELYKILKN CFFPMKRVLA RPEEDVEEEY RLFAIPNADD RDVESIAEEQ
LRMSFASING SATSVVTHHG KKERYRRQR
//
