ID A0A062XV95_9BACT Unreviewed; 720 AA.
AC A0A062XV95;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=EG19_06050 {ECO:0000313|EMBL:KDA53309.1};
OS Thermoanaerobaculum aquaticum.
OC Bacteria; Acidobacteriota; Thermoanaerobaculia; Thermoanaerobaculales;
OC Thermoanaerobaculaceae; Thermoanaerobaculum.
OX NCBI_TaxID=1312852 {ECO:0000313|EMBL:KDA53309.1, ECO:0000313|Proteomes:UP000027284};
RN [1] {ECO:0000313|EMBL:KDA53309.1, ECO:0000313|Proteomes:UP000027284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP-01 {ECO:0000313|EMBL:KDA53309.1,
RC ECO:0000313|Proteomes:UP000027284};
RA Stamps B.W., Losey N.A., Lawson P.A., Stevenson B.S.;
RT "The Genome Sequence of Thermoanaerobaculum aquaticum MP-01, The First
RT Cultivated Group 23 Acidobacterium.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDA53309.1}.
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DR EMBL; JMFG01000023; KDA53309.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A062XV95; -.
DR STRING; 1312852.EG19_06050; -.
DR OrthoDB; 9779858at2; -.
DR Proteomes; UP000027284; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00882; Ras_like_GTPase; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF00025; Arf; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000027284}.
FT DOMAIN 499..720
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 249..280
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 458..489
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 720 AA; 78072 MW; 8747F91238379AA6 CRC64;
MVQFDNQYRQ VKLKIVYYGP ALGGKTTCLQ YIHRVTDPQR RTRLYTLNTA SDRTLFFDLL
GLDLGRIRGY RLTVQLFTVP GQVQYNTTRR AVLAGADGVV FVADSQVGQE KANLESLQNL
QENLKANGLD PETIPLVFQY NKRDLPKILS RAELDRLLNP KGYPVFETVA TTGQGVLEAF
AAICEATVLS VADRLGITAQ ADALTRLVAN VRAAMAPLIP TKPPEVEAPV VIRTTSEGQL
GPEELMAEAV RANAAMADLS ARLDQLSKQL SRRVEELQAL LVFSQVLTQA REPDEVTTAF
FERFLVDMKV TAGTLILENP KGELVEVLRR GLAAEPLMRP GAQGELPARA ILEGRQAFRL
DLGDLAPGQN REPWIDEVRG LGFEHFLAVP LVAQDRAWGL VTAYGEASRG PFQDEDLELA
AIMGAVGAVA IANARAWHAL EQVNRNLENL VAARTGELQQ ALAKAEALAK ELSVKNQELE
ATYRRLAELD QLKGELLRRV AHELNTPVTA IQTAARILTR WDQIPKEKVS NFVGIVAEEA
SRLGDLIASA LQAAALGLPQ EVGEKTAVPV ADLLRQALAP VKGEVAERQI KVAVKVASGL
DKVMCFPEAL TAALTALLKN AVEFSRPQGS VTVTVLPVRK AGQNFVEFRV EDNGVGIAPE
DLPQVTEPFF QGGNLLTGKP KGLGLGLTVA KRVAELHGGS LEIVSQPEQG TTVSLRVAVG
//
