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Database: UniProt
Entry: A0A066RNJ6_9GAMM
LinkDB: A0A066RNJ6_9GAMM
Original site: A0A066RNJ6_9GAMM 
ID   A0A066RNJ6_9GAMM        Unreviewed;       464 AA.
AC   A0A066RNJ6;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-SEP-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:KDM92035.1};
GN   ORFNames=EA58_08455 {ECO:0000313|EMBL:KDM92035.1};
OS   Photobacterium galatheae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Photobacterium.
OX   NCBI_TaxID=1654360 {ECO:0000313|EMBL:KDM92035.1, ECO:0000313|Proteomes:UP000027192};
RN   [1] {ECO:0000313|EMBL:KDM92035.1, ECO:0000313|Proteomes:UP000027192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S2753 {ECO:0000313|EMBL:KDM92035.1,
RC   ECO:0000313|Proteomes:UP000027192};
RA   Machado H.R., Gram L.;
RT   "Draft genome sequence of Photobacterium halotolerans S2753: a
RT   solonamide, ngercheumicin and holomycin producer.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KDM92035.1}.
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DR   EMBL; JMIB01000015; KDM92035.1; -; Genomic_DNA.
DR   RefSeq; WP_036751225.1; NZ_JMIB01000015.1.
DR   EnsemblBacteria; KDM92035; KDM92035; EA58_08455.
DR   Proteomes; UP000027192; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000027192};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897}.
FT   DOMAIN      161    363       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      372    441       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     169    176       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   464 AA;  52464 MW;  77CA1E06397833AC CRC64;
     MSSSLWLQCL QRLQEELPAT EFSMWVRPLQ AELNDNTLTL FAPNRFVLDW VRDKYLNSIN
     RLLNEFCGAD APMLRFEVGS KPVTAPPPQP AAAVAVGTAH DKIDPPSPTW EPAPSPVQPE
     SAKGYRSNVN PKHNFNNFVE GKSNQLGLAA CRQVADNPGA AYNPLFLYGG TGLGKTHLLH
     AVGNAIADRK PNAKVVYMHS ERFVQDMVKA LQNNAIEEFK RYYRSVDALL IDDIQFFANK
     ERSQEEFFHT FNALLEGNQQ IILTSDRYPR EISGVEDRLK SRFGWGLTVA IEPPELETRV
     AILMKKAEDH HIRLADEVAF FIAKRLRSNV RELEGALNRV IANANFTGRA ITIDFVREAL
     RDLLALQEKL VTIDNIQKTV AEYYKIKMAD MLSKRRSRSV ARPRQMAMAL AKELTNHSLP
     EIGDAFGGRD HTTVLHACRK IEQLREESHD IKEDYSNLIR TLSS
//
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