ID A0A066XLS6_COLSU Unreviewed; 2226 AA.
AC A0A066XLS6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Putative Sec63 Brl domain-containing protein {ECO:0000313|EMBL:KDN66985.1};
GN ORFNames=CSUB01_06887 {ECO:0000313|EMBL:KDN66985.1};
OS Colletotrichum sublineola (Sorghum anthracnose fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=1173701 {ECO:0000313|EMBL:KDN66985.1, ECO:0000313|Proteomes:UP000027238};
RN [1] {ECO:0000313|Proteomes:UP000027238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TX430BB {ECO:0000313|Proteomes:UP000027238};
RX PubMed=24926053; DOI=10.1128/genomeA.00540-14;
RA Baroncelli R., Sanz-Martin J.M., Rech G.E., Sukno S.A., Thon M.R.;
RT "Draft genome sequence of Colletotrichum sublineola, a destructive pathogen
RT of cultivated sorghum.";
RL Genome Announc. 2:E0054014-E0054014(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDN66985.1}.
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DR EMBL; JMSE01000859; KDN66985.1; -; Genomic_DNA.
DR STRING; 1173701.A0A066XLS6; -.
DR eggNOG; KOG0951; Eukaryota.
DR HOGENOM; CLU_000335_1_0_1; -.
DR OMA; QTEIQYY; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000027238; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProt.
DR CDD; cd18019; DEXHc_Brr2_1; 1.
DR CDD; cd18021; DEXHc_Brr2_2; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041094; Brr2_helicase_PWI.
DR InterPro; IPR048863; BRR2_plug.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF4; U5 SMALL NUCLEAR RIBONUCLEOPROTEIN HELICASE; 1.
DR Pfam; PF21188; BRR2_plug; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF18149; Helicase_PWI; 1.
DR Pfam; PF02889; Sec63; 2.
DR PIRSF; PIRSF039073; BRR2; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000027238}.
FT DOMAIN 536..720
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 758..967
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1387..1563
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 31..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2207..2226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..217
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..272
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2212..2226
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2226 AA; 251942 MW; 6FDB30C9F2BFEB7B CRC64;
MSNQDQHRDV SQYKYSAMSN LVLQADRRFV SRRNDEATGD PESLAGKLSI RDMGARVARE
SAPKQKKPTG LPDVERGRLQ EGEDVLAREQ RKKKGETAQP RGAGVLGTGD LLVEGIRYRP
RTPATRATFE LILKIVSDNL GDVPQTAVIS AADVTLEFLK DDDLKDTEKK REIDDLLGVS
MSAKEFNELV NLGKKITDYD AQDEDEDMDD NATDADGDEL DERQGVAVVF EDSEDEEGGI
VNEVREESSE DEDADENEEP PAADAQEADE PDDDAMVIDS APKKQTQDAK QSKTVSARDI
DAFWLQRQIG KLYTDSHEQH DKTTDALRLL SGEPDEQGGD EKSLREIEND LMELFDYEHH
ELVQLLIENR EKVVWLTRHS RAETDEQRAV IEREMASEGL QWILNEKFGK KTDDQKGRKM
EIKMDLDAPS SVANAPPAES ERPQGLVGGL QPRKLINLEN LVFDQGNHLM SNPKVRLPEG
STKRTFKGYE EIHVPAPKKR SDPGDTLVPI TEMPEWSRLP FGTTKSLNKI QSKCYPTAFG
DDGNMLICAP TGSGKTNVAM LTILREIGKN RNPETGDIDL DAFKIVYIAP LKALVQEQVG
NFGKRLEPYG VKVSELTGDR QLTKQQIAET QIIVTTPEKW DVITRKATDL TYTNLVRLVI
IDEIHLLHDD RGPVLESIVS RTIRKTEQTG EPVRLVGLSA TLPNYKDVAS FLRVDINTGL
FHFDGSFRPC PLRQEFIGVT DRKAIKQLKT MNDVTYNKVI EHVGANRNQM LIFVHSRKET
AKTARYIRDK ALEMDTINQI LRHDAGSREV LNEAASQATD KDLKDILPYG FGIHHAGMNR
IDRTDVEDLF ARGAIQVLVC TATLAWGVNL PAHTVIIKGT SVYSPEKGSW VELSPQDVLQ
MLGRAGRPQF DTYGEGIIIT TQNEIQYYLS LLNQQLPIES QFVSRLVDNL NAEIVLGNVR
SRDEGVEWLG YTYLFVRMLR SPGLYQVGAE YEDDGALEQM RVDLIHSAAS VLRKSNLVKY
DEKTGRLQST ELGRIASHYY ITHGSMETYN NLIQPSITTI ELFRVFSLSA EFKYIPVRQD
EKLELAKLLG RVPIPVKESI EEPHAKINVL LQAYISRLKL DGLALMADMV YVTQSAGRIL
RAIFEITMKK GWASVAKTAL DLCKMAEKRM WPTMSPLRQF PGCPRDIVQK AERIEVPWSN
YFDLDPPRMG ELLGMPKAGR TVCSLVAKFP RVEVQAQVQP LTRSMLRVEL SISPNFEWDV
EVHGPAESFW IFVEDCDGED ILFSDQFLLR KEYAESESNE HIVDFTVPIT EPMPPNYFIS
VISDRWMHSE TRLPVSFHKL ILPERFPPHT ELLELQPLPV AALKAKEYAK LYPNWDHFNR
IQTQTFNSLY NTDQNVFVGA PTGSGKTVCA EFALLRHWAK ADAGRAVYIA PFQELVDLRL
DDWQKRLSGL RGGKTIEKLT GETTTDLKIL ERSDLVLATP IQWDVLSRQW KRRKNVSTVE
LFIADEVHLL GNQMGYVYEI IVSRMHYIRT QTELPMRIIA LGVSLANARD LGEWIDAKKH
DIYNFSPHVR PVPLELHIQS YTNPHFPSLM LSMAKPTYLA ITQMSADKPA IVFVPSRKQT
RATTRDLLTA AFMDDDEDRF LHAEVEQMRP LLDRVSEEAL AEALSHGVGY YHEALSQSDK
RIVKHLYEHG AIQVLVASRD VCWELNSTAH LVVVMGTQYF EGREHRYIDY SLSEILHMFG
KALRASKDGR GRGVLMLPAA KRDFYKKFLN EALPVESHLH NYLHDAFVTE ISTKMIESGD
DAINWTTFTY FYRRLLANPS FYSLTSTTQE GLSDYMSDLI QTTLQELSDS KIIELDEDDG
SVAPQNAAMI AAYYNISYIT MQTFLLSLSA KTKLKGVLEI VTSATEFEAI QIRRHEEGIL
RRIYDRIPVK MAEPVYDSAH FKAFVLLQAH FSRMQLPIDL AKDQEVIVSK VLSLLSATVD
ILSSDGHLNA MNAMEMSQMV VQAMWDRDSP LKQIPHFTPE VVKVANEFGY VSSSSLILNG
ANLDFFHSVK DIFDFMEAMN PDENPDYAKL VKRLGLSQKQ LGEAAAFTND KYPDIELEHS
ILDEEEIRAN EPAYLSVQIQ RQVDEDGEFD PTVHAPFYPA KKLENWWLVI GEEATKNLLA
IKRVTIGREL KVKLEFTVPT AGNHDLKLFL MSDSYVGVDQ EREFSITAAE GMDVDDSDEE
EEEDEE
//
