ID A0A067BQ68_SAPPC Unreviewed; 1037 AA.
AC A0A067BQ68;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=SPRG_12986 {ECO:0000313|EMBL:KDO20629.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO20629.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO20629.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO20629.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KK583307; KDO20629.1; -; Genomic_DNA.
DR RefSeq; XP_012208683.1; XM_012353293.1.
DR AlphaFoldDB; A0A067BQ68; -.
DR STRING; 695850.A0A067BQ68; -.
DR EnsemblProtists; KDO20629; KDO20629; SPRG_12986.
DR GeneID; 24134897; -.
DR KEGG; spar:SPRG_12986; -.
DR VEuPathDB; FungiDB:SPRG_12986; -.
DR OMA; WEALEWY; -.
DR OrthoDB; 52367at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR024862; TRPV.
DR PANTHER; PTHR10582:SF2; INACTIVE; 1.
DR PANTHER; PTHR10582; TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00248; ANK; 6.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 4.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 538..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 580..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..699
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 711..732
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 744..765
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 771..791
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 812..831
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 837..857
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 869..892
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 199..231
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 232..254
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 266..298
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 300..327
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 709..900
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT COILED 975..1009
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1037 AA; 114654 MW; 93471CFFE690A41F CRC64;
MRIAAAEPEP DGENASTVVH VLHSARALAG AATRIQAWYQ LFRRRTSFAV VREKYLQLLA
TIGDDHVGVL RKWYCIYLQC RRPQARRAST AHAASWEVVS VATMRRTLQP LPPNASEEVL
YAFLEALPSR WLVVDWTHLD DMARHGGEEE DDDDNDDDEM RPQDTLLHIV VRRCSNVSRA
CLDLFQHNDS TSLQHLGAHD QSIVHAAAEG GHLRTLQALL VAGGDMRATD IVGATPLHLA
AANGHVAIVQ YLAEMMHMPL DVTTQSGETP LHFAATHNHT SVVGYLLSQK CNLNAVTTTQ
FCSSLHYAAA RGHLDVVKQL VMAHADVLPN AVGNTILHVA AETNDTAILA YLSSLPAMVH
FATAANNRGY SPLHVAAVHG AKDAYVLLNR NPWRSKPPLG LITDYEGLFP FALLVQSDGI
TTEDAVGLYL PRHAGSDDVP MWHACVFQQV LHTAPDFAWA VLDAYAIAAT NHVGAPALTM
PKLDEMYGAD IESSLLGMVL DCVDDASKSH RSVLLRLLQH PIPSRILRVK WKSFGRRIYY
MQLFGAALLL ATLTIGIAMA RPAPRTPTTS ANATQPAATF YLSLFLWIDF VLVSIAGMLI
SYAYERVLQY VRHGVIRFLR VTKAAVTSPR FFATSRHLET KGPKKGGYVR RRLKELLLRH
CVSPTTPSTA LVNNVLAIGL LTVTTSIAGW LTLCVLFGLG SATDASPRTT FLSLNLAVQW
LATLYMLAWE ALEWYGAPRR YATSIWNFVQ VVVFCTLLLL PLSAASDETH GTLLAPLVLL
SYLNFLELLR FHDWTGPMIS MVHYMLRDVR NFLVLYAVFQ MGLTCAYYAL LQGQLGFATF
SEAFVSTYLI MFGLGNADVM LRSAPYPQQY VLTVCFMLHF LVVVIVLLNA LIATMTKSTD
AILDQVQDQV ACNRARTILR AEVTVPHRIR TSLWNRLKAR VTKRGDSYLF KPTTVPKTAV
EATEDPGNKD DSAAMQALET RLVQCVDTIE SLRRAQEDME ARLLAESAKT QDALAALTAL
LAQPRARKLK LTDVEAR
//
