ID A0A067BVB1_SAPPC Unreviewed; 788 AA.
AC A0A067BVB1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
GN ORFNames=SPRG_12669 {ECO:0000313|EMBL:KDO22173.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO22173.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO22173.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO22173.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
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DR EMBL; KK583273; KDO22173.1; -; Genomic_DNA.
DR RefSeq; XP_012207111.1; XM_012351721.1.
DR AlphaFoldDB; A0A067BVB1; -.
DR STRING; 695850.A0A067BVB1; -.
DR EnsemblProtists; KDO22173; KDO22173; SPRG_12669.
DR GeneID; 24134611; -.
DR KEGG; spar:SPRG_12669; -.
DR VEuPathDB; FungiDB:SPRG_12669; -.
DR OMA; MHITIDE; -.
DR OrthoDB; 335467at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0070290; F:N-acylphosphatidylethanolamine-specific phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd09105; PLDc_vPLD1_2_like_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR015679; PLipase_D_fam.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR PANTHER; PTHR18896:SF60; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022963};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..788
FT /note="phospholipase D"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001633793"
FT TRANSMEM 635..660
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 449..476
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 788 AA; 86670 MW; A2750DDAAB8111E9 CRC64;
MRSRGVVLTL CAASAAGFVT CTRSTSLTEI FTNWCICQPC NLCSYTLFQG CDVLLTNAVS
TSDGSDIPTR QPLLAPSDWF LTADEITNSR GGVPRTSLAT SSSGNFMHIF ADTSSTFAAI
HHDLLTAHAA YFTSWTLGDI PYLPHIDPAI TFKSTWGKAI TTNGLSAHGL VWSNLPELDR
VTDMHAWMNS LTPSHGARVQ LMTDDRVTSI TGSLHQKSLV LSIDNQLWAY AGGMDQAFDR
WDTKYHNESA LRNAAAIRTN NNGWIDVHSR VLGPAAVDIL HNFLDRWNDP KPPGPALGPP
FVTPPMPLQA SWNVPQNFFS SAALLSSLAI NTSAGPHDVQ ILRTFSCNYH GYASFAPHGE
TSILAGRIKA IRNAKNYIYI EDQYFVYMPD LFHELLAILP TLQRLVVFTV TPGKLERASG
YAKYQYDMIN PLLQKFPNKV QIYIPKPSLG IYVHSKVLLV DDVLVSIGSS NWNVRSMTSD
AEIGQQIVDT TRVIVENDIQ GTKLAHDFRI SKFGELTNFT VDFANLSFLQ AANALETYAQ
RSDAWIEPYM LYEKPYWAIY GAGAKNLVDG DGRCTSAVPL SLCKNDTWLQ AQYQVIQITC
SCELAGIAVT KCDNMTDYLN AGQASAEAAF INKALLYYGG IFAGVSLGVL LVVCGCCCYG
RKWHRNRRKQ AVSPVAKRGQ YLAGGTPPVP VGILTFAHQQ QQYSSSLMLA RRFVSTQRTL
VKEASVASVL PKAESQSLFR DHSNDRLQPA TSTPARSVKS LQSVYSLQYL NGESASKPFD
VPSSKLQK
//
